Roulet Tiffany, Zdanowicz Nicolas
Université Catholique de Louvain, Faculty of Medicine, 1200 Bruxelles, Belgium,
Psychiatr Danub. 2017 Sep;29(Suppl 3):219-221.
Delusional parasitosis (DP) is an uncommon psychiatric disorder. Patients suffering from this disorder have the fixed false belief of being infested by a parasite. Because of this condition, patients mainly consult with dermatologists or general practitioners. They are often reluctant to see a psychiatrist and to take treatment with antipsychotics because of their belief. The following describes the case of a woman who has the particularity that the DP started a few days after sertraline interruption. This situation raises the question of the impact of the sertraline interruption on pruritus and its role as a trigger of DP.
Case report description and research on medline, pubmed with the keyword: delusional parasitosis, Ekbom syndrome, pruritus, SSRI.
Any other pathology that could explain the patient's symptomatology was excluded which allows us to diagnose this patient with DP. The disappearance of the symptoms was obtained with 200 mg of sertraline and 2 mg of risperidone. It appears that pruritus can be favored by cutaneous dryness due to age and anxiety. Symptoms of discontinuation of SSRIs may include anxiety and paresthesia.
The main hypothesis explaining the onset of DP would be the raise of paresthesia followed by the interruption of sertraline (discontinuation symptom) on a favorable field, which means an elderly woman of an anxious nature and having cutaneous dryness. It therefore seems necessary to discuss the discontinuation symptoms at the initiation of a treatment for this kind of patient to avoid false interpretations of skin symptoms such as paresthesia or itching.
妄想性寄生虫病(DP)是一种罕见的精神疾病。患有这种疾病的患者坚信自己感染了寄生虫。因此,患者主要咨询皮肤科医生或全科医生。由于他们的信念,他们往往不愿看精神科医生或接受抗精神病药物治疗。以下描述了一名女性的病例,其特殊性在于妄想性寄生虫病在舍曲林中断服用几天后开始出现。这种情况引发了关于舍曲林中断对瘙痒的影响及其作为妄想性寄生虫病触发因素的作用的问题。
病例报告描述以及在医学在线(Medline)、美国国立医学图书馆生物医学期刊数据库(PubMed)上使用关键词“妄想性寄生虫病、埃克波姆综合征、瘙痒、选择性5-羟色胺再摄取抑制剂(SSRI)”进行研究。
排除了任何其他可解释患者症状的病理情况,从而得以诊断该患者患有妄想性寄生虫病。使用200毫克舍曲林和2毫克利培酮后症状消失。似乎由于年龄和焦虑导致的皮肤干燥会加重瘙痒。选择性5-羟色胺再摄取抑制剂停药症状可能包括焦虑和感觉异常。
解释妄想性寄生虫病发病的主要假说是,在一个有利的背景下,感觉异常增加,随后舍曲林中断(停药症状),这意味着是一名性格焦虑且皮肤干燥的老年女性。因此,对于这类患者,在开始治疗时似乎有必要讨论停药症状,以避免对诸如感觉异常或瘙痒等皮肤症状的错误解读。