Endoscopy. 2018 Feb;50(2):137-141. doi: 10.1055/s-0043-119286. Epub 2017 Sep 27.
Relief from dysphagia and regurgitation are the main goals of therapy in symptomatic Zenker's diverticulum. Flexible endoscopic treatment has proved to be an effective and safe method in control of these symptoms. The aim of our study was to further improve the resection of the cricopharyngeal muscle using a new technique, the double incision and snare resection (DISR) procedure, to reduce the recurrence rate.
From February 2016 to April 2017, 16 patients were treated with 18 DISR procedures at our institution. The symptoms of the patients were recorded by a seven-item questionnaire prior to treatment, and re-evaluation was scheduled at 1 and 6 months after treatment.
The median age was 70 years (range 55 - 85), and 10 patients were men (62 %). The median size of the diverticulum was 20 mm (range 5 - 40 mm), and the DISR procedure was performed in 28 minutes (range 20 - 47 minutes), with no major postinterventional complications. All patients re-started oral nutrition on the day after the intervention; a gastric tube was not required. The median follow-up was 3 months (range 1 - 15 months). Two patients received a planned second-step procedure, one because of a very large cricopharyngeal muscle and one because of a cyst inside the Zenker's bridge. Although one patient suffered from mild recurrence of symptoms, she refused a second treatment. All other patients were free of symptoms after treatment.
The DISR procedure is a new endoscopic treatment technique that safely and reproducibly offers relief from symptomatic Zenker's diverticulum.
缓解吞咽困难和反流是症状性Zenker 憩室治疗的主要目标。灵活的内镜治疗已被证明是控制这些症状的有效且安全的方法。我们的研究目的是通过一种新的技术,即双切口和圈套切除术(DISR)进一步提高环咽肌切除术的效果,以降低复发率。
2016 年 2 月至 2017 年 4 月,我院采用 18 次 DISR 手术治疗了 16 名患者。在治疗前,患者通过一个七项问卷记录了他们的症状,并在治疗后 1 个月和 6 个月安排了重新评估。
中位年龄为 70 岁(范围 55-85 岁),10 名患者为男性(62%)。憩室的中位大小为 20mm(范围 5-40mm),DISR 手术时间为 28 分钟(范围 20-47 分钟),无重大介入后并发症。所有患者均在干预后次日重新开始口服营养,无需胃管。中位随访时间为 3 个月(范围 1-15 个月)。两名患者接受了计划中的第二步手术,一名患者因环咽肌非常大,另一名患者因 Zenker 桥内有囊肿。尽管有一名患者出现轻度症状复发,但她拒绝了第二次治疗。所有其他患者在治疗后均无症状。
DISR 手术是一种新的内镜治疗技术,可安全且可重复地缓解症状性 Zenker 憩室。