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嗜酸性粒细胞性心肌炎:一种常常较为隐匿且可能未被充分认识的现象。

Eosinophilic myocarditis: an often subtle and potentially under-recognised phenomenon.

作者信息

Coughlan John Joseph, Fitzgerald Gerald Paul, Gul Filza, Liston Richard

机构信息

Department of Cardiology, University Hospital Limerick, Limerick, Ireland.

Department of Cardiology, Mercy University Hospital, Cork, Munster, Ireland.

出版信息

BMJ Case Rep. 2017 Sep 27;2017:bcr-2017-221289. doi: 10.1136/bcr-2017-221289.

Abstract

A 34-year-old woman presented to our service with chest pain, a troponin rise and dynamic ECG changes. Of note, she had complained of fatigue, feeling constitutionally unwell and a generalised rash in the days prior to her presentation. Her echocardiogram showed normal wall motion and preserved ejection fraction. Her eosinophil count, normal at presentation, rose to a peak of 12.21×10/L. She was haemodynamically stable throughout with no evidence clinically of congestive cardiac failure. CT coronary angiogram showed no obstructive coronary artery disease. Cardiac MRI demonstrated areas of late gadolinium enhancement consistent with myocarditis. A diagnosis of eosinophilic myocarditis was made. No tissue biopsy was performed due to the patchy myocardial involvement and high potential for low-yield biopsy. Our patient was treated conservatively and has made an excellent recovery.

摘要

一名34岁女性因胸痛、肌钙蛋白升高及动态心电图改变前来我院就诊。值得注意的是,她在就诊前几天曾抱怨疲劳、身体不适及全身性皮疹。她的超声心动图显示室壁运动正常,射血分数保留。她的嗜酸性粒细胞计数在就诊时正常,升至峰值12.21×10/L。她在整个过程中血流动力学稳定,临床上无充血性心力衰竭的证据。CT冠状动脉造影显示无阻塞性冠状动脉疾病。心脏磁共振成像显示钆延迟强化区域与心肌炎相符。诊断为嗜酸性粒细胞性心肌炎。由于心肌受累呈斑片状且活检阳性率低的可能性高,未进行组织活检。我们的患者接受了保守治疗,恢复良好。

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