Chawla Tabish, Bari Hassaan, Effendi Shahrukh
Aga Khan University Hospital, Karachi, Pakistan.
Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2017 Oct;67(10):1621-1624.
Whipple's pancreaticoduodenectomy has been refined over the years to be a safe operation though the morbidity rate still remains high (30-50%). Pancreatic fistula is the most important cause of mortality following pancreaticoduodenectomy. To prevent it, surgeons have used two anastomotic techniques: pancreaticojejunostomy and pancreaticogastrostomy. Recent studies found that pancreaticogastrostomy is associated with fewer overall complications than pancreaticojejunostomy. This is a retrospective review of patients who underwent Whipple's at Aga Khan University Hospital and had pancreaticogastrostomy as a preferred anastomosis for pancreatic stump. Forty four patients met the inclusion criteria, 27 were male. No patient developed post-operative pancreatic fistula, 13 (31%) patients had morbidities including delayed gastric emptying 4(9.1%), wound infection 3(6.8%), and haemorrhage 6(13.6%). Mortality is reported to be 5 (11.9%). Pancreaticogastrostomy seems to be a safe alternative and easier anastomosis to perform with less post-operative morbidity and mortality. Further data should become available with greater numbers in the future. .
多年来,惠普尔胰十二指肠切除术已得到改进,成为一种安全的手术,尽管其发病率仍然很高(30%-50%)。胰瘘是胰十二指肠切除术后死亡的最重要原因。为预防胰瘘,外科医生采用了两种吻合技术:胰空肠吻合术和胰胃吻合术。最近的研究发现,与胰空肠吻合术相比,胰胃吻合术的总体并发症更少。这是一项对在阿迦汗大学医院接受惠普尔手术且将胰胃吻合术作为胰残端首选吻合方式的患者的回顾性研究。44例患者符合纳入标准,其中27例为男性。没有患者发生术后胰瘘,13例(31%)患者出现并发症,包括胃排空延迟4例(9.1%)、伤口感染3例(6.8%)和出血6例(13.6%)。据报告死亡率为5例(11.9%)。胰胃吻合术似乎是一种安全的替代方法,且操作更容易,术后发病率和死亡率更低。未来随着病例数的增加,应该会有更多数据。