Granström L, Backman L, Uvnäs-Moberg K
Department Surgery, Danderyd Hospital, Stockholm, Sweden.
Acta Chir Scand. 1988 Feb;154(2):117-21.
The postprandial secretion of insulin, gastrin and somatostatin was studied in 23 extremely obese subjects and nine normal-weight controls after a liquid test meal. Apart from a significantly higher insulin level in the obese group, no significant intergroup difference was found. The effect of weight loss on the same hormones was studied in 18 patients 6 months after gastric banding. The mean weight loss during this period was 33 +/- 2.1 (SEM) kg. There was significant decrease in postprandial insulin secretion after gastric banding, but neither gastrin nor somatostatin levels were altered.
对23名极度肥胖受试者和9名体重正常的对照者在摄入流食试验餐后的胰岛素、胃泌素和生长抑素餐后分泌情况进行了研究。除肥胖组胰岛素水平显著较高外,未发现组间有显著差异。对18名接受胃束带手术6个月后的患者,研究了体重减轻对相同激素的影响。在此期间平均体重减轻33±2.1(标准误)kg。胃束带手术后餐后胰岛素分泌显著减少,但胃泌素和生长抑素水平均未改变。