Nurmikko T, Pertovaara A, Pöntinen P J
Department of Neurology, University Central Hospital, University of Tampere, Finland.
Acupunct Electrother Res. 1987;12(3-4):185-91. doi: 10.3727/036012987816358841.
The effect D-phenylalanine (DPA), a putative inhibitor of enkephalin degradation, on the two separate pain components produced by the submaximal effort tourniquet test was evaluated in healthy human volunteers (N = 8). DPA attenuated the increase of the intensity of the ischemic and pressure pain components with increasing ischemia duration, but only the effect on the pressure pain component was significant. The results support some earlier reports suggesting that DPA has analgetic properties.
在健康人类志愿者（N = 8）中评估了一种假定的脑啡肽降解抑制剂D-苯丙氨酸（DPA）对次最大用力止血带试验产生的两种独立疼痛成分的影响。随着缺血持续时间的增加，DPA减弱了缺血性疼痛成分和压力性疼痛成分强度的增加，但仅对压力性疼痛成分的影响具有统计学意义。这些结果支持了一些早期报告，表明DPA具有镇痛特性。
