Ciavattini Andrea, Clemente Nicolò, Delli Carpini Giovanni, Saccardi Carlo, Borgato Shara, Litta Pietro
Woman's Health Sciences Department, Gynecologic Section, Università Politecnica delle Marche, Via F. Corridoni 11, 60123, Ancona, Italy.
Department of Woman and Child Health, Università di Padova, Padua, Italy.
Arch Gynecol Obstet. 2017 Dec;296(6):1167-1173. doi: 10.1007/s00404-017-4545-z. Epub 2017 Sep 27.
Laparoscopic myomectomy is the uterus-preserving surgical approach of choice in case of symptomatic fibroids. However, it can be a difficult procedure even for an experienced surgeon and can result in excessive blood loss, prolonged operating time and postoperative complications. A combined approach with laparoscopic uterine artery occlusion and simultaneous myomectomy was proposed to reduce these complications. The aim of this study was to evaluate the safety and efficacy of the combined laparoscopic approach in women with symptomatic "large" intramural uterine fibroids, compared to the traditional laparoscopic myomectomy alone.
Prospective nonrandomized case-controlled study of women who underwent a conservative surgery for symptomatic "large" (≥ 5 cm in the largest diameter) intramural uterine fibroids. The "study group" consisted of women who underwent the combined approach (laparoscopic uterine artery bipolar coagulation and simultaneous myomectomy), while women who underwent the traditional laparoscopic myomectomy constituted the "control group". A comparison between the two groups was performed, and several intraoperative and postoperative outcomes were evaluated.
No significant difference in the overall duration of surgery between women of the "study group" and "control group" emerged; however, a significantly shorter surgical time for myomectomy was observed in the "study group". The intraoperative blood loss and the postoperative haemoglobin drop were significantly lower in the "study group". No difference in the postoperative pain between groups emerged, and the postoperative hospital stay was similar in the two groups.
The laparoscopic uterine artery bipolar coagulation and simultaneous myomectomy is a safe and effective procedure, even in women with symptomatic "large" intramural uterine fibroids, with the benefit of a significant reduction in the intraoperative blood loss when compared to the traditional laparoscopic myomectomy.
对于有症状的子宫肌瘤,腹腔镜子宫肌瘤切除术是首选的保留子宫的手术方法。然而,即使对于经验丰富的外科医生来说,这也可能是一个困难的手术,并且可能导致失血过多、手术时间延长和术后并发症。有人提出采用腹腔镜子宫动脉闭塞联合同期子宫肌瘤切除术来减少这些并发症。本研究的目的是评估与单纯传统腹腔镜子宫肌瘤切除术相比,联合腹腔镜手术方法对有症状的“大”肌壁间子宫肌瘤女性的安全性和有效性。
对因有症状的“大”(最大直径≥5 cm)肌壁间子宫肌瘤接受保守手术的女性进行前瞻性非随机病例对照研究。“研究组”由接受联合手术方法(腹腔镜子宫动脉双极电凝和同期子宫肌瘤切除术)的女性组成,而接受传统腹腔镜子宫肌瘤切除术的女性构成“对照组”。对两组进行比较,并评估了一些术中及术后结果。
“研究组”和“对照组”女性的手术总时长没有显著差异;然而,“研究组”的子宫肌瘤切除手术时间明显更短。“研究组”的术中失血量和术后血红蛋白下降幅度明显更低。两组术后疼痛没有差异,两组的术后住院时间相似。
腹腔镜子宫动脉双极电凝和同期子宫肌瘤切除术是一种安全有效的手术方法,即使对于有症状的“大”肌壁间子宫肌瘤女性也是如此,与传统腹腔镜子宫肌瘤切除术相比,其优点是术中失血量显著减少。