Department of Obstetrics and Gynecology, Jinhua Hospital of Zhejiang University, Jinhua, China.
Department of Obstetrics and Gynecology, Jinhua Hospital of Zhejiang University, Jinhua, China.
J Minim Invasive Gynecol. 2018 Mar-Apr;25(3):434-439. doi: 10.1016/j.jmig.2017.06.032. Epub 2017 Sep 21.
To compare the surgical technique of temporary bilateral uterine artery blockage with titanium clips in laparoscopic myomectomy with traditional surgery for uterine myomas to determine efficacy, ability to control bleeding, and recurrence.
Randomized, controlled, prospective study (Canadian Task Force classification I).
Obstetrics and gynecology department in Jinhua Municipal Central Hospital.
Women with symptomatic uterine myoma.
Sixty-four patients with symptomatic uterine myomas were randomly divided into trial (group A, n = 33) and control groups (group B, n = 31). Temporary bilateral uterine artery occlusion and myomectomy were used in group A and laparoscopic myomectomy only in group B. Operative time, perioperative bleeding, follow-up relief of menorrhagia, and recurrence of myomas were evaluated.
All patients in this study underwent successful laparoscopic operation without intraoperative complications. Operative time between groups was not significantly different (p = .255 in single-myoma group and p = .811 in multiple-myoma group), blood loss in group A was notably lower than the conventional surgery group (p < .001). At final follow-up (2 years), recurrence rate and menorrhagia symptom relief were not statistically significant (p = .828 and p > .999, respectively). The fertility index of antimüllerian hormone showed no statistical difference between groups preoperatively or at 2 days, 3 months, 6 months, and 1 year postoperatively (p = .086, p = .247, p = .670, p = .753, and p = .857, respectively).
Temporary bilateral uterine artery occlusion during laparoscopic myomectomy does not increase mean operative time, offers a possible option to reduce blood loss effectively, improves menorrhagia, and does not impact recurrence rate compared with conventional surgery.
比较腹腔镜子宫肌瘤剔除术中临时双侧子宫动脉阻断术与传统手术治疗子宫肌瘤的手术技术、止血效果和复发情况。
随机、对照、前瞻性研究(加拿大卫生研究院分类 I 级)。
金华市中心医院妇产科。
有症状的子宫肌瘤患者。
将 64 例有症状的子宫肌瘤患者随机分为试验组(A 组,n = 33)和对照组(B 组,n = 31)。A 组采用临时双侧子宫动脉阻断和子宫肌瘤剔除术,B 组仅采用腹腔镜子宫肌瘤剔除术。评估手术时间、围手术期出血量、随访时月经过多缓解情况和子宫肌瘤复发情况。
本研究所有患者均成功完成腹腔镜手术,无术中并发症。两组患者的手术时间无显著差异(单发肌瘤组 p = .255,多发肌瘤组 p = .811),A 组术中出血量明显低于传统手术组(p < .001)。末次随访(2 年)时,复发率和月经过多症状缓解率无统计学差异(p = .828 和 p > .999)。术前及术后 2 天、3 个月、6 个月和 1 年,抗苗勒管激素的生育指数两组间无统计学差异(p = .086、p = .247、p = .670、p = .753 和 p = .857)。
与传统手术相比,腹腔镜子宫肌瘤剔除术中临时双侧子宫动脉阻断不会增加手术时间,可有效减少出血量,改善月经过多,且不影响复发率。