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一名意大利女性心脏直视手术后发生播散性嵌合体分枝杆菌感染:病例报告及文献综述

Disseminated Mycobacterium chimaera infection after open heart surgery in an Italian woman: a case report and a review of the literature.

作者信息

Chiesi Sheila, Piacentini Daniela, Salerno Nicola Duccio, Luise Dora, Peracchi Marta, Concia Ercole, Cazzadori Angelo, Piovan Enrico, Lanzafame Massimiliano

机构信息

Infectious Diseases Department, University Hospital of Verona, Verona, Italy.

Unit of Microbiology and Virology, University Hospital of Padova, Padova, Italy.

出版信息

Infez Med. 2017 Sep 1;25(3):267-269.

PMID:28956545
Abstract

We report the first Italian case of Mycobacterium chimaera disseminated infection in a patient with a history of cardiac surgery. The patient was initially diagnosed with sarcoidosis and started on immunosuppressive therapy. Ten months later she developed a vertebral osteomyelitis: M. chimaera was isolated from bone specimen. A review of the literature shows that M. chimaera infection occurs specifically in this population of patients, due to contamination of heater-cooler units used during cardiosurgery. Devices responsible for the transmission were produced by Sorin Group Deutschland. Mycobacterium chimaera infection should be included in the differential diagnosis for patients undergoing cardiac surgery.

摘要

我们报告了意大利首例有心脏手术史患者发生的播散性嵌合分枝杆菌感染病例。该患者最初被诊断为结节病,并开始接受免疫抑制治疗。十个月后,她患上了脊椎骨髓炎:从骨标本中分离出了嵌合分枝杆菌。文献综述表明,由于心脏手术期间使用的热交换器受到污染,嵌合分枝杆菌感染特别容易在这类患者群体中发生。传播感染的设备由德国索林集团生产。心脏手术患者的鉴别诊断应包括嵌合分枝杆菌感染。

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