Ganatra Sarju, Sharma Ajay, D'Agostino Richard, Gage Thomas, Kinnunen Paula
LAHEY HOSPITAL & MEDICAL CENTER, BURLINGTON, MASSACHUSETTS.
Methodist Debakey Cardiovasc J. 2018 Oct-Dec;14(4):301-302. doi: 10.14797/mdcj-14-4-301.
Mycobacterium chimaera (M. chimaera) is a slow-growing nontuberculous mycobacteria usually associated with pulmonary infection in immunocompromised patients. Attributed to a specific brand of contaminated heater-cooler units used during cardiac surgery, M. chimaera has become a global public health concern due to disseminated infection affecting immunocompetent hosts. Given its nonspecific presenting symptoms and indolent course of infection, M. chimaera can mimic and be misdiagnosed as sarcoidosis. Increased awareness among the medical community and at-risk population should be maintained to facilitate more rapid diagnosis and prevent inappropriate treatment of this potentially devastating condition.
嵌合体分枝杆菌（M. chimaera）是一种生长缓慢的非结核分枝杆菌，通常与免疫功能低下患者的肺部感染有关。由于心脏手术中使用的特定品牌的加热器-冷却器装置受到污染，嵌合体分枝杆菌已成为全球公共卫生问题，因为它会引起播散性感染，影响免疫功能正常的宿主。鉴于其非特异性的临床表现和隐匿的感染过程，嵌合体分枝杆菌可能会被误诊为结节病。应提高医学界和高危人群的认识，以促进更快速的诊断，并防止对这种可能具有毁灭性的疾病进行不恰当的治疗。
