The Irish Longitudinal Study on Ageing, Trinity College Dublin, Ireland.
The Department of Biochemistry & Clinical Pathology, St James's Hospital, Dublin, Ireland.
J Gerontol A Biol Sci Med Sci. 2018 Mar 14;73(4):519-525. doi: 10.1093/gerona/glx168.
Few data are available examining the determinants of vitamin D status exclusively in older adults. We aimed to investigate the prevalence and determinants of vitamin D deficiency in a representative sample of the older Irish population (aged 50-98 years).
The concentration of 25-hydroxyvitamin D (25(OH)D) was measured in 5,356 community-dwelling older Irish adults from The Irish Longitudinal Study on Ageing (TILDA). Detailed demographic, geographic, lifestyle, and socioeconomic factors were assessed by questionnaire. Proportions of deficiency prevalence were generated by season sampled. Linear regression was used to investigate the association between 25(OH)D concentration and reported risk factors.
The prevalence of deficiency (25(OH)D < 30 nmol/L) was 13.1% (95% CI: 12.1-14.2). Deficiency status was more prevalent in nonsupplement users, in winter, in smokers, in obese adults, the physically inactive, those living alone, and in the oldest old (>80 years). The main predictors (p < .05) of 25(OH)D concentration were supplement use (coefficient nmol/L: 27.2 [95% CI: 15.3-39.2]), smoking (-8.9 [-12.6--5.2]), summer season (5.9 [2.7-9.1]), and obesity (-4.0 [-6.3--1.7]).
Vitamin D deficiency is common among older Irish adults. These data indicate the need for targeted strategies within sections of the older population to improve vitamin D status.
关于专门针对老年人的维生素 D 状况决定因素的研究数据很少。我们旨在调查具有代表性的爱尔兰老年人群（年龄在 50-98 岁之间）中维生素 D 缺乏症的流行率及其决定因素。
在爱尔兰老龄化纵向研究（TILDA）中，对 5356 名居住在社区的爱尔兰老年人测量了 25-羟维生素 D（25（OH）D）的浓度。通过问卷调查评估了详细的人口统计学，地理，生活方式和社会经济因素。按季节采样生成了缺乏症的流行率。线性回归用于调查 25（OH）D 浓度与报告的危险因素之间的关联。
缺乏症（25（OH）D <30nmol/L）的患病率为 13.1％（95％CI：12.1-14.2）。在不使用补充剂，冬季，吸烟者，肥胖者，不活跃者，独居者和最老年人（>80 岁）中，缺乏症的发生率更高。25（OH）D 浓度的主要预测因素（p <0.05）是补充剂的使用（nmol/L 系数：27.2 [95％CI：15.3-39.2]），吸烟（-8.9 [-12.6--5.2]），夏季（5.9 [2.7-9.1]）和肥胖（-4.0 [-6.3--1.7]）。
维生素 D 缺乏症在爱尔兰老年人中很常见。这些数据表明，需要针对老年人群中的某些人群制定有针对性的策略，以改善维生素 D 状况。
