Wang Yanting, Mo Xueyin, Zhang Jinglu, Fan Yuan, Wang Kelun, Peter Svensson
a Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Department of Endodontics , Affiliated Hospital of Stomatology, Nanjing Medical University , Nanjing , China.
b Yixing Institute of Preventive Dentistry , Yixing , China.
Acta Odontol Scand. 2018 Jan;76(1):58-63. doi: 10.1080/00016357.2017.1383511. Epub 2017 Sep 28.
To establish a preliminary thermal and mechanical somatosensory profile using a standardized quantitative sensory testing (QST) to investigate site, gender and age differences in healthy Chinese.
Twenty younger (age: 20-40 years, 10 men, 10 women) and twenty older (age: 41-61 years, 10 men, 10 women) healthy participants completed the study. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical detection threshold (MDT) and mechanical pain threshold (MPT) were measured at five sites: Left hand, bilaterally at the mental area, tip of tongue and the lower lip mucosa. Mixed model ANOVAs with repeated measures were used to analyze the data.
MDT(p < .001) and MPT (p < .05) were significantly higher on the hand compared to the mental areas. The CDT ( p = .006) was significantly higher and WDT (p < .001) was significantly lower at the tongue compared to lip mucosa and CDT (p < .001) was higher at the tongue mucosa than at the mental areas. WDT (p < .001) and HPT (p < .05) were significantly higher at the tip of the tongue and the lower lip mucosa compared to the mental areas. Significantly lower sensitivity for WDT (p < .001) and CDT (p = .004) were found in the older group compared to the younger group. Significant gender differences were found with less sensitivity for WDT (p = .024) and MDT (p = .003) in men compared to women.
Application of standardized QST can provide valuable information of orofacial somatosensory phenotypes in a Chinese population. Age, gender and site are mandatory to control for.
采用标准化定量感觉测试（QST）建立初步的热觉和机械性躯体感觉概况，以研究健康中国人在部位、性别和年龄方面的差异。
20名年轻（年龄：20 - 40岁，男性10名，女性10名）和20名年长（年龄：41 - 61岁，男性10名，女性10名）健康参与者完成了本研究。在五个部位测量冷觉检测阈值（CDT）、温觉检测阈值（WDT）、冷痛阈值（CPT）、热痛阈值（HPT）、机械觉检测阈值（MDT）和机械痛阈值（MPT）：左手、双侧颏部、舌尖和下唇黏膜。采用重复测量的混合模型方差分析来分析数据。
与颏部相比，手部的MDT（p < 0.001）和MPT（p < 0.05）显著更高。与唇黏膜相比，舌尖的CDT（p = 0.006）显著更高，WDT（p < 0.001）显著更低，且舌尖黏膜的CDT（p < 0.001）高于颏部。与颏部相比，舌尖和下唇黏膜的WDT（p < 0.001）和HPT（p < 0.05）显著更高。与年轻组相比，年长组的WDT（p < 点击此处添加链接文本0.001）和CDT（p = 0.004）敏感性显著降低。发现显著的性别差异，男性的WDT（p = 0.024）和MDT（p = 0.003）敏感性低于女性。
应用标准化QST可为中国人群的口腔颌面部躯体感觉表型提供有价值的信息。年龄、性别和部位是必须加以控制的因素。
