Gale R P, Reisner Y
Department of Medicine, UCLA School of Medicine 90024.
Lancet. 1988 Apr 23;1(8591):923-6. doi: 10.1016/s0140-6736(88)91724-2.
The probability that bone-marrow transplantation will be beneficial after nuclear accidents depends on several factors, including circumstances of the accident, degree of damage in other body systems, and radiation dose. Transplant-related variables, such as donor-recipient histocompatibility and post-transplant immune suppression, are also important. The benefits of transplantation may result from transient or permanent haemopoietic reconstitution. The balance of potential benefits versus risks should be individually calculated for each accident and each patient; generalisations are likely to result in untenable conclusions.
核事故后进行骨髓移植是否有益取决于多个因素，包括事故情况、身体其他系统的损伤程度以及辐射剂量。与移植相关的变量，如供体-受体组织相容性和移植后的免疫抑制，也很重要。移植的益处可能源于短暂或永久性的造血重建。对于每一次事故和每一位患者，都应单独计算潜在益处与风险的平衡；一概而论可能会得出站不住脚的结论。
