猫软脑膜血管的自身调节反应。

Autoregulatory response of pial vessels in the cat.

作者信息

Auer L M, Pucher R, Leber K, Ishiyama N

机构信息

Department of Neurosurgery, University of Graz, Austria.

出版信息

Neurol Res. 1987 Dec;9(4):245-8. doi: 10.1080/01616412.1987.11739803.

DOI:10.1080/01616412.1987.11739803

PMID:2895901

Abstract

Pial vessel responses to mean arterial pressures (MAP) between 40 and 160 mmHg, induced by withdrawal and reinfusion of blood, were studied in twelve cats under barbiturate- and N2O-anaesthesia, using the cranial window technique and videoangiometry. Very minor changes of pial arterial calibres were noted between MAP 80 and 120 mmHg. During further reduction of MAP, small arteries dilated more than large arteries and measured 43 +/- 4.6% and 30 +/- 1.9% at MAP 40 mmHg, respectively. When MAP was elevated to 140 mmHg, large arteries constricted more than small ones; at MAP 160 mmHg, however, they started to redilate, while small arteries continued to constrict to -13 +/- 2.3%. Within the autoregulatory range, pial veins remained unchanged; at MAPs of 40 and 160 mmHg, venous calibre variations remained below 10%.

摘要

在巴比妥类药物和一氧化二氮麻醉下，对12只猫采用颅窗技术和视频血管造影术，研究了通过抽血和回输血液诱导的平均动脉压（MAP）在40至160 mmHg之间时软脑膜血管的反应。在MAP为80至120 mmHg之间时，软脑膜动脉口径变化非常小。在MAP进一步降低期间，小动脉比大动脉扩张更明显，在MAP为40 mmHg时分别测量为43±4.6%和30±1.9%。当MAP升高到140 mmHg时，大动脉比小动脉收缩更明显；然而，在MAP为160 mmHg时，大动脉开始再次扩张，而小动脉继续收缩至-13±2.3%。在自动调节范围内，软脑膜静脉保持不变；在MAP为40和160 mmHg时，静脉口径变化保持在10%以下。