Wang Kun, Tian Zhongbin, Chen Junfan, Liu Jian, Wang Yang, Zhang Hongqi, Wang Jun, Zhang Yisen, Yang Xinjian
Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Department of Neurosurgery, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, China.
Front Neurol. 2017 Sep 14;8:482. doi: 10.3389/fneur.2017.00482. eCollection 2017.
We aimed to evaluate the risk factors of recurrence after stent(s)-assisted coiling (SAC) of intracranial vertebrobasilar dissecting aneurysms (VBDAs) based on 168 consecutive patients.
Between January 2011 and December 2015, 168 consecutive patients with 170 intracranial VBDAs, which were treated by SAC, were recruited from four high-volume centers. We used multivariate logistic regression to examine factors that affected recurrence of VBDAs.
The mean duration of clinical follow-up of the 168 patients was 7.81 months (range, 3-24 months). Of the 168 patients, 4 (2.38%) suffered from intraoperative complications and 16 (9.52%) had postoperative complications. Two (1.19%) had severe disability. Imaging follow-up was available for 168 patients (170 VBDAs), with a mean duration 7.81 months, and 24 (14.12%) cases of recurrence of aneurysms were noted. Aneurysm size and metal coverage of stent(s) at the neck were independent predictors of recurrence after SAC by logistic regression analysis.
This multicenter cohort study shows that aneurysm size and the metal coverage of stent(s) at aneurysmal neck are independent factors associated with recurrence of VBDAs after SAC.
我们旨在基于168例连续患者评估颅内椎基底动脉夹层动脉瘤(VBDAs)支架辅助弹簧圈栓塞术(SAC)后复发的危险因素。
2011年1月至2015年12月期间,从四个大型中心招募了168例连续的颅内VBDAs患者,共170个动脉瘤接受了SAC治疗。我们使用多因素逻辑回归分析来研究影响VBDAs复发的因素。
168例患者的临床随访平均时长为7.81个月(范围3 - 24个月)。168例患者中,4例(2.38%)发生术中并发症,16例(9.52%)发生术后并发症。2例(1.19%)出现严重残疾。168例患者(170个VBDAs)均进行了影像学随访,平均时长7.81个月,发现24例(14.12%)动脉瘤复发。经逻辑回归分析,动脉瘤大小和瘤颈处支架的金属覆盖率是SAC术后复发的独立预测因素。
这项多中心队列研究表明,动脉瘤大小和瘤颈处支架的金属覆盖率是与SAC术后VBDAs复发相关的独立因素。