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颅内椎动脉夹层的血管内治疗

Endovascular Treatment of Intracranial Vertebral Artery Dissection.

作者信息

Chung Joonho, Cheol Lim Yong, Sam Shin Yong

机构信息

Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Department of Neurosurgery, Ajou University College of Medicine and Hospital, Suwon, Korea.

出版信息

J Neuroendovasc Ther. 2021;15(5):265-280. doi: 10.5797/jnet.ra.2020-0150. Epub 2021 Jan 11.

Abstract

Intracranial vertebral artery dissection (VAD) is the most common arterial dissection in intracranial arteries. Some types of VAD can heal spontaneously after reconstitution of the vessel lumen with excellent prognosis, whereas others can progress to stroke that needs treatment. Recently, endovascular treatment (EVT) has emerged and is suggested as a treatment option for VADs due to perceived low rates of procedure-related morbidity with good efficacy. In the last decade, we have accumulated our strategies to treat those VADs. Here, we try to share our experiences about VADs, including indications and methods of treatment of VADs using EVT. We perform EVT for ruptured VADs presenting with SAH and some of unruptured VADs such as VAD with recurrent or progressive ischemia, dissecting aneurysm larger than 7 mm or with mass effect, early ugly change of VADs in shape and size during follow-up period, involving the basilar artery (BA) and bilateral VADs. We present how we have done in our real practice for the last decade for treating VADs by EVT rather than reviewing and organizing so-far-published literature. We tended to occlude the rupture point by vertebral artery (VA) occlusion in non-dominant VA or stent-assisted coiling in dominant VA for ruptured VADs. We tended to reconstruct original hemodynamics using various stents for unruptured VADs. To decide what to treat and how to treat are very complicated for VADs. However, we believe that EVT is the current mainstay for treating VADs. Each technique of EVT should be determined on a case-by-case basis at the discretion of endovascular neurosurgeons and/or interventional neuroradiologists according to presenting symptoms, hemodynamic status, including sufficiency of the collateral supply and anatomic features of the vertebrobasilar artery as well as the posterior inferior cerebellar artery, anterior spinal artery, and medullary perforators.

摘要

颅内椎动脉夹层(VAD)是颅内动脉中最常见的动脉夹层。某些类型的VAD在血管腔重建后可自发愈合,预后良好,而其他类型则可能进展为需要治疗的中风。近年来,血管内治疗(EVT)应运而生,并因其被认为与手术相关的发病率较低且疗效良好,而被建议作为VAD的一种治疗选择。在过去十年中,我们积累了治疗这些VAD的策略。在此,我们试图分享我们关于VAD的经验,包括使用EVT治疗VAD的适应证和方法。我们对伴有蛛网膜下腔出血(SAH)的破裂VAD以及一些未破裂VAD进行EVT治疗,如伴有反复或进行性缺血的VAD、直径大于7mm或有占位效应的夹层动脉瘤、随访期间VAD在形状和大小上出现早期不良变化、累及基底动脉(BA)和双侧VAD。我们介绍的是过去十年我们在实际临床中如何通过EVT治疗VAD,而不是回顾和整理已发表的文献。对于破裂的VAD,我们倾向于在非优势侧椎动脉进行椎动脉(VA)闭塞以封闭破裂点,在优势侧椎动脉进行支架辅助弹簧圈栓塞。对于未破裂的VAD,我们倾向于使用各种支架重建原始血流动力学。对于VAD,决定治疗方案和治疗方式非常复杂。然而,我们认为EVT是目前治疗VAD的主要方法。血管内神经外科医生和/或介入神经放射科医生应根据患者的症状、血流动力学状态(包括侧支循环的充分性)以及椎基底动脉、小脑后下动脉、脊髓前动脉和延髓穿支动脉的解剖特征,逐案决定EVT的具体技术。

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