• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Fragmentation of Oligosaccharides from Sodium Adduct Molecules Depends on the Position of -Acetyl Hexosamine Residue in Their Sequences in Mass Spectrometry.质谱分析中，来自钠加合物分子的寡糖片段化取决于其序列中N-乙酰己糖胺残基的位置。
Mass Spectrom (Tokyo). 2017;6(Spec Iss 2):S0073. doi: 10.5702/massspectrometry.S0073. Epub 2017 Sep 22.
2
Amino and acetamide functional group effects on the ionization and fragmentation of sugar chains in positive-ion mass spectrometry.氨基和乙酰胺官能团对正离子质谱中糖链电离和碎裂的影响。
J Am Soc Mass Spectrom. 2014 Jan;25(1):95-103. doi: 10.1007/s13361-013-0739-1. Epub 2013 Oct 24.
3
Analysis of neutral oligosaccharides for structural characterization by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry.采用基质辅助激光解吸/电离四极杆离子阱飞行时间质谱对中性寡糖进行结构表征分析。
J Mass Spectrom. 2005 Mar;40(3):380-8. doi: 10.1002/jms.798.
4
Structural characterization of synthetic poly(ester amide) from sebacic acid and 4-amino-1-butanol by matrix-assisted laser desorption ionization time-of-flight/time-of-flight tandem mass spectrometry.通过基质辅助激光解吸电离飞行时间/飞行时间串联质谱法对由癸二酸和4-氨基-1-丁醇合成的聚（酯酰胺）进行结构表征。
Rapid Commun Mass Spectrom. 2008;22(6):739-54. doi: 10.1002/rcm.3417.
5
Semiquantitative analysis of isomeric oligosaccharides by negative-ion mode UV-MALDI TOF postsource decay mass spectrometry and their fragmentation mechanism study at N-acetyl hexosamine moiety.负离子模式紫外基质辅助激光解吸电离飞行时间后源衰变质谱法对异构寡糖的半定量分析及其在N-乙酰己糖胺部分的裂解机理研究
J Mass Spectrom. 2006 Apr;41(4):454-62. doi: 10.1002/jms.1001.
6
Quantitative aspects in electrospray ionization ion trap and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of malto-oligosaccharides.寡麦芽糖的电喷雾电离离子阱和基质辅助激光解吸/电离飞行时间质谱中的定量问题。
Rapid Commun Mass Spectrom. 2011 Aug 15;25(15):2201-8. doi: 10.1002/rcm.5105.
7
Determination of the fatty acyl profiles of phosphatidylethanolamines by tandem mass spectrometry of sodium adducts.通过钠加合物的串联质谱法测定磷脂酰乙醇胺的脂肪酰基谱。
Rapid Commun Mass Spectrom. 2008 Oct;22(20):3238-44. doi: 10.1002/rcm.3727.
8
Structural characterization of 2-aminobenzamide-derivatized oligosaccharides using a matrix-assisted laser desorption/ionization two-stage time-of-flight tandem mass spectrometer.使用基质辅助激光解吸/电离二级飞行时间串联质谱仪对2-氨基苯甲酰胺衍生化寡糖进行结构表征。
Rapid Commun Mass Spectrom. 2005;19(14):2075-84. doi: 10.1002/rcm.2033.
9
Fragmentation characteristics of permethylated oligosaccharides using a matrix-assisted laser desorption/ionization two-stage time-of-flight (TOF/TOF) tandem mass spectrometer.使用基质辅助激光解吸/电离二级飞行时间（TOF/TOF）串联质谱仪分析全甲基化低聚糖的碎片化特征
Rapid Commun Mass Spectrom. 2004;18(22):2637-49. doi: 10.1002/rcm.1668.
10
Linkage and sequence analysis of neutral oligosaccharides by negative-ion MALDI tandem mass spectrometry with laser-induced dissociation.采用负离子 MALDI 串联质谱与激光诱导解离技术对中性寡糖进行连锁和序列分析。
Anal Chim Acta. 2019 Sep 13;1071:25-35. doi: 10.1016/j.aca.2019.04.067. Epub 2019 Apr 29.

引用本文的文献

1
Safety of 3-fucosyllactose (3-FL) produced by a derivative strain of K-12 DH1 as a novel food pursuant to Regulation (EU) 2015/2283.根据欧盟法规（EU）2015/2283，由K-12 DH1衍生菌株生产的3-岩藻糖基乳糖（3-FL）作为新型食品的安全性。
EFSA J. 2023 Jun 8;21(6):e08026. doi: 10.2903/j.efsa.2023.8026. eCollection 2023 Jun.
2
Safety of 3-fucosyllactose (3-FL) produced by a derivative strain of BL21 (DE3) as a Novel Food pursuant to Regulation (EU) 2015/2283.根据欧盟法规（EU）2015/2283，由BL21（DE3）衍生菌株生产的3-岩藻糖基乳糖（3-FL）作为新型食品的安全性。
EFSA J. 2022 May 25;20(5):e07329. doi: 10.2903/j.efsa.2022.7329. eCollection 2022 May.

本文引用的文献

1
Probing the catalytic site of rabbit muscle glycogen phosphorylase using a series of specifically modified maltohexaose derivatives.使用一系列经过特殊修饰的麦芽六糖衍生物探测兔肌肉糖原磷酸化酶的催化部位。
Glycoconj J. 2017 Aug;34(4):563-574. doi: 10.1007/s10719-017-9776-5. Epub 2017 Jun 8.
2
Amino and acetamide functional group effects on the ionization and fragmentation of sugar chains in positive-ion mass spectrometry.氨基和乙酰胺官能团对正离子质谱中糖链电离和碎裂的影响。
J Am Soc Mass Spectrom. 2014 Jan;25(1):95-103. doi: 10.1007/s13361-013-0739-1. Epub 2013 Oct 24.
3
Tandem mass spectra of glycan substructures enable the multistage mass spectrometric identification of determinants on oligosaccharides.糖链亚结构的串联质谱能够实现寡糖上决定簇的多级质谱鉴定。
Rapid Commun Mass Spectrom. 2013 May 15;27(9):931-9. doi: 10.1002/rcm.6527.
4
Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 1999-2000.基质辅助激光解吸/电离质谱法分析碳水化合物和糖缀合物：1999 - 2000年的最新进展
Mass Spectrom Rev. 2006 Jul-Aug;25(4):595-662. doi: 10.1002/mas.20080.
5
Strategy for simulation of CID spectra of N-linked oligosaccharides toward glycomics.用于糖组学的N-连接寡糖CID光谱模拟策略
J Proteome Res. 2006 Apr;5(4):808-14. doi: 10.1021/pr0503937.
6
A strategy for identification of oligosaccharide structures using observational multistage mass spectral library.一种使用观测多阶段质谱库鉴定寡糖结构的策略。
Anal Chem. 2005 Aug 1;77(15):4719-25. doi: 10.1021/ac048350h.
7
Fragmentation of negative ions from carbohydrates: part 1. Use of nitrate and other anionic adducts for the production of negative ion electrospray spectra from N-linked carbohydrates.碳水化合物负离子的碎片化：第1部分。使用硝酸盐和其他阴离子加合物从N-连接碳水化合物产生负离子电喷雾光谱。
J Am Soc Mass Spectrom. 2005 May;16(5):622-30. doi: 10.1016/j.jasms.2005.01.004.
8
Structural assignment of isomeric 2-aminopyridine-derivatized oligosaccharides using MSn spectral matching.使用MSn光谱匹配对异构2-氨基吡啶衍生化寡糖进行结构归属
Rapid Commun Mass Spectrom. 2004;18(4):385-91. doi: 10.1002/rcm.1341.
9
Structural characterization of oligosaccharides using MALDI-TOF/TOF tandem mass spectrometry.使用基质辅助激光解吸电离飞行时间串联质谱法对寡糖进行结构表征。
Anal Chem. 2003 Sep 15;75(18):4895-903. doi: 10.1021/ac0341968.
10
Distinguishing of linkage isomers of lactotetra oligosaccharides by using the relative ion intensity analysis of post-source decay fragment ions in curved-field reflectron matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.利用弯曲场反射器基质辅助激光解吸/电离飞行时间质谱中源后衰变碎片离子的相对离子强度分析来区分乳糖四糖的连接异构体。
Anal Sci. 2001 Jan;17(1):83-7. doi: 10.2116/analsci.17.83.

质谱分析中，来自钠加合物分子的寡糖片段化取决于其序列中N-乙酰己糖胺残基的位置。

Fragmentation of Oligosaccharides from Sodium Adduct Molecules Depends on the Position of -Acetyl Hexosamine Residue in Their Sequences in Mass Spectrometry.

作者信息

Yamagaki Tohru, Makino Yasushi

机构信息

Bioorganic Research Institute, Suntory Foundation for Life Sciences.

Department of Chemistry, Graduate School of Science, Osaka Prefecture University.

出版信息

Mass Spectrom (Tokyo). 2017;6(Spec Iss 2):S0073. doi: 10.5702/massspectrometry.S0073. Epub 2017 Sep 22.

DOI:10.5702/massspectrometry.S0073
PMID:28959518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5610956/
Abstract

Six different sequences of hexasaccharides, pyridylaminated malto-hexaoses containing one -acetyl hexosamine (HexNAc) residue, were analyzed using matrix-assisted laser desorption/ionization (MALDI) tandem time-of-flight (TOF) mass spectrometry (MS). Based on the product ion spectra of sodium adducts [M+Na], the chemical species of the observed product ions contained a HexNAc residue and had high ion abundance, indicating that the HexNAc residue had a higher affinity to sodium atom than glucopyranose. The acetamide group coordinated easily to sodium atom. This general rule of product ion generation was useful to predict the structure of the oligosaccharides based on the MS/MS product ion spectra.

摘要

使用基质辅助激光解吸/电离（MALDI）串联飞行时间（TOF）质谱（MS）分析了六种不同序列的六糖，即含有一个N-乙酰己糖胺（HexNAc）残基的吡啶基化麦芽六糖。基于钠加合物[M+Na]的产物离子光谱，观察到的产物离子的化学种类含有一个HexNAc残基且离子丰度高，表明HexNAc残基对钠原子的亲和力高于葡萄糖吡喃糖。乙酰胺基团易于与钠原子配位。这种产物离子生成的一般规则有助于根据MS/MS产物离子光谱预测寡糖的结构。