Choe Young June, Park Young Joon, Kim Ju Whi, Eom Hye Eun, Park Ok, Oh Myoung Don, Lee Jong Koo
Seoul Center for Infectious Disease Control, Seoul, Korea.
Department of Epidemiology, Graduate School of Public Health, Seoul National University, Seoul, Korea.
J Korean Med Sci. 2017 Nov;32(11):1876-1878. doi: 10.3346/jkms.2017.32.11.1876.
Measles has been declared eliminated from the Korea since 2006. In April 2014, a measles outbreak occurred at a University in Seoul. A total of 85 measles cases were identified. In order to estimate vaccine effectiveness of measles vaccine, we reviewed the vaccination records of the university students. The vaccine effectiveness of two doses of measles containing vaccine was 60.0% (95% CI, 38.2-74.1; P < 0.05). Transmission was interrupted after the introduction of outbreak-response immunization. The outbreak shows that pockets of under-immunity among college students may have facilitated the disease transmission despite the high 2-dose vaccination coverage in the community.
自2006年起，韩国已宣布消除麻疹。2014年4月，首尔一所大学发生了麻疹疫情。共确诊85例麻疹病例。为评估麻疹疫苗的有效性，我们查阅了大学生的疫苗接种记录。两剂含麻疹疫苗的疫苗有效性为60.0%（95%可信区间，38.2 - 74.1；P < 0.05）。引入疫情应对免疫措施后，传播得以中断。此次疫情表明，尽管社区两剂疫苗接种覆盖率很高，但大学生中存在的免疫空白可能助长了疾病传播。
