色素性视网膜炎患者的葡萄膜炎：30 年连续数据。

Uveitis in Patients with Retinitis Pigmentosa: 30 Years' Consecutive Data.

机构信息

a Department of Uvea , Sankara Ntethralaya , Chennai , India.

b Department of Vitreoretinal Services , Aditya Birla Sankara Nethralaya Mukundapur , Kolkata , India.

出版信息

Ocul Immunol Inflamm. 2018;26(8):1283-1288. doi: 10.1080/09273948.2017.1348527. Epub 2017 Sep 29.

DOI:10.1080/09273948.2017.1348527

PMID:28960116

Abstract

PURPOSE

To describe the clinical pattern of uveitis in patients with retinitis pigmentosa (RP) at a tertiary care eye hospital over a period of 30 years.

METHODS

The medical records of 32 eyes of 22 patients of RP with uveitis were included in this study. Collected data included age, subsets of uveitis, best corrected visual acuities (BCVA), detailed laboratory investigations, and treatment.

RESULTS

Mean age at presentation was 53.4 ± 18.8 years, and mean age of diagnosis of RP was 39.2 ± 21.4 years. Uveitis was bilateral in 10 (45.5%) patients. The most common of uveitis in current study was anterior uveitis (56.2%), followed by intermediate uveitis (43.8%). Cataract developed in 12 (37.5%) eyes, and three eyes had raised intraocular pressure. Ten patients (45.5%) required oral steroid, and one patient required oral methotrexate.

CONCLUSIONS

Uveitis in RP patients is rare, but not uncommon. Coexistence of these disorders might support the inflammatory pathway in etiology of RP.

摘要

目的

描述一家三级眼科医院在 30 年期间患有色素性视网膜炎（RP）的患者的葡萄膜炎临床特征。

方法

本研究纳入了 22 名 RP 合并葡萄膜炎患者的 32 只眼的病历。收集的数据包括年龄、葡萄膜炎亚组、最佳矫正视力（BCVA）、详细的实验室检查和治疗情况。

结果

发病时的平均年龄为 53.4±18.8 岁，RP 的平均诊断年龄为 39.2±21.4 岁。10 名患者（45.5%）的葡萄膜炎为双侧性。本研究中最常见的葡萄膜炎是前葡萄膜炎（56.2%），其次是中间葡萄膜炎（43.8%）。12 只眼（37.5%）发生白内障，3 只眼眼压升高。10 名患者（45.5%）需要口服类固醇，1 名患者需要口服甲氨蝶呤。