相似文献
1
Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease.
Trends Neurosci. 2017 Oct;40(10):592-602. doi: 10.1016/j.tins.2017.08.003.
2
Endosomal-lysosomal dysfunctions in Alzheimer's disease: Pathogenesis and therapeutic interventions.
Metab Brain Dis. 2021 Aug;36(6):1087-1100. doi: 10.1007/s11011-021-00737-0. Epub 2021 Apr 21.
3
Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment.
Sci Aging Knowledge Environ. 2006 Jun 28;2006(10):re2. doi: 10.1126/sageke.2006.10.re2.
4
Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.
FASEB J. 2017 Jul;31(7):2729-2743. doi: 10.1096/fj.201700359.
5
Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease.
Mol Psychiatry. 2016 May;21(5):707-16. doi: 10.1038/mp.2015.97. Epub 2015 Jul 21.
6
Retromers in Alzheimer's disease.
Neurodegener Dis. 2012;10(1-4):116-21. doi: 10.1159/000335910. Epub 2012 Mar 3.
7
Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up.
Am J Pathol. 2004 Mar;164(3):757-61. doi: 10.1016/S0002-9440(10)63163-X.
8
Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions.
Biochem J. 2016 Jul 15;473(14):1977-93. doi: 10.1042/BCJ20160147.
9
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking.
J Neuroinflammation. 2017 Feb 2;14(1):29. doi: 10.1186/s12974-017-0803-z.
10
Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.
Curr Protein Pept Sci. 2017;18(7):687-701. doi: 10.2174/1389203717666160311121246.
引用本文的文献
1
An integrated view of the relationships between amyloid, tau, and inflammatory pathophysiology in Alzheimer's disease.
Alzheimers Dement. 2025 Aug;21(8):e70404. doi: 10.1002/alz.70404.
2
Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation.
Nat Commun. 2025 Jul 30;16(1):6990. doi: 10.1038/s41467-025-61802-1.
3
Dysregulated calcium signaling in the aged primate association cortices: vulnerability to Alzheimer's disease neuropathology.
Front Aging Neurosci. 2025 Jul 15;17:1610350. doi: 10.3389/fnagi.2025.1610350. eCollection 2025.
4
Alzheimer's genetic risk factor Bin1 controls synapse vesicle exo-endocytosis in inhibitory synapses.
Cell Rep. 2025 Aug 26;44(8):116005. doi: 10.1016/j.celrep.2025.116005. Epub 2025 Jul 15.
5
Linking endo-lysosomal pH, sterol, and trafficking to neurodegenerative disease.
FEMS Yeast Res. 2025 Jan 30;25. doi: 10.1093/femsyr/foaf034.
6
Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.
Proc Natl Acad Sci U S A. 2025 Jul 8;122(27):e2501111122. doi: 10.1073/pnas.2501111122. Epub 2025 Jun 30.
7
Bend it like BIN1: how a membrane-curving adaptor protein shapes cardiac physiology.
Am J Physiol Heart Circ Physiol. 2025 Jul 1;329(1):H94-H108. doi: 10.1152/ajpheart.00198.2025. Epub 2025 May 20.
8
Organelle perturbation in Alzheimer's disease: do intracellular amyloid-ß and the fragmented Golgi mediate early intracellular neurotoxicity?
Front Cell Dev Biol. 2025 Apr 15;13:1550211. doi: 10.3389/fcell.2025.1550211. eCollection 2025.
9
Research progress of extracellular vesicles derived from mesenchymal stem cells in the treatment of neurodegenerative diseases.
Front Immunol. 2025 Apr 2;16:1496304. doi: 10.3389/fimmu.2025.1496304. eCollection 2025.
10
Exosomes as Therapeutic and Diagnostic Tools: Advances, Challenges, and Future Directions.
Cell Biochem Biophys. 2025 Mar 24. doi: 10.1007/s12013-025-01730-5.
本文引用的文献
1
Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy.
Eur J Hum Genet. 2017 Aug;25(8):973-981. doi: 10.1038/ejhg.2017.87. Epub 2017 May 24.
2
BACE inhibitor bust in Alzheimer trial.
Nat Rev Drug Discov. 2017 Mar 1;16(3):155. doi: 10.1038/nrd.2017.43.
3
Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease.
Ann Clin Transl Neurol. 2016 Oct 20;3(12):934-939. doi: 10.1002/acn3.339. eCollection 2016 Dec.
4
Genomic variants, genes, and pathways of Alzheimer's disease: An overview.
Am J Med Genet B Neuropsychiatr Genet. 2017 Jan;174(1):5-26. doi: 10.1002/ajmg.b.32499.
5
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
EMBO Rep. 2017 Jan;18(1):102-122. doi: 10.15252/embr.201642738. Epub 2016 Nov 28.
6
Loss of Bin1 Promotes the Propagation of Tau Pathology.
Cell Rep. 2016 Oct 18;17(4):931-940. doi: 10.1016/j.celrep.2016.09.063.
7
Vps35-dependent recycling of Trem2 regulates microglial function.
Traffic. 2016 Dec;17(12):1286-1296. doi: 10.1111/tra.12451. Epub 2016 Nov 1.
8
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
PLoS One. 2016 Sep 13;11(9):e0161969. doi: 10.1371/journal.pone.0161969. eCollection 2016.
9
The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.
Sci Rep. 2016 Aug 1;6:30654. doi: 10.1038/srep30654.
10
Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease.
BMC Neurosci. 2016 Jul 18;17(1):50. doi: 10.1186/s12868-016-0288-1.
Zotero 插件