Dhillon Rana S, Smith Paul D
Department of Neurosurgery, St. Vincent's Hospital, Melbourne, Australia; Centre for Clinical Neuroscience and Neurological Research, Melbourne, Australia.
Department of Neurosurgery, St. Vincent's Hospital, Melbourne, Australia; Centre for Clinical Neuroscience and Neurological Research, Melbourne, Australia; Department of Surgery, University of Melbourne, Melbourne, Australia.
World Neurosurg. 2018 Jan;109:138-139. doi: 10.1016/j.wneu.2017.09.132. Epub 2017 Sep 27.
Varicella zoster virus remains dormant in the dorsal root ganglia after childhood exposure to chickenpox. Its reactivation results in herpes zoster, otherwise known as shingles, which is a painful vesicular rash in a dermatomal distribution. We present a case of foraminal disk extrusion that resulted in radicular pain in a dermatomal distribution. The resultant inflammatory response around the dorsal root ganglion triggered an episode of shingles, which elegantly highlights the pathophysiology of this condition at a gross anatomic level.
水痘带状疱疹病毒在儿童期感染水痘后潜伏于背根神经节。其再激活会导致带状疱疹，即俗称的缠腰龙，表现为沿皮节分布的疼痛性水疱疹。我们报告一例椎间孔椎间盘突出导致沿皮节分布的神经根性疼痛的病例。背根神经节周围由此产生的炎症反应引发了带状疱疹发作，这在大体解剖层面很好地凸显了该病的病理生理学机制。
