Department of Research and Development, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.
Primary Care, Stoke-on-Trent Clinical Commissioning Group, Stoke-on-Trent, UK.
BMJ Open. 2017 Sep 28;7(9):e015278. doi: 10.1136/bmjopen-2016-015278.
To evaluate the feasibility and potential clinical benefits of medicines optimisation through comprehensive geriatric assessment (CGA) of frail patients with multiple conditions, by secondary care geriatricians in a general practice care setting.
Seven general practitioner (GP) practices in one region of Stoke-on-Trent volunteered to take part. GPs selected patients (n=186) who were local permanent residents, at least 65 years old and on eight or more medications per day. Patients were sent a written invitation outlining the assessment purpose/format. Prior to patient assessments, primary care staff prepared packs detailing patient medical history, recent consultations, current medications, recent laboratory tests and social circumstances. One hour was allocated for the CGA per patient, with one of three geriatricians, to enable sufficient time to explore all relevant aspects. Assessment comprised a full history, thorough clinical examination, assessment of balance and mobility, mental function and information on home environment and support arrangements. After consultation, geriatricians made recommendations regarding further assessments, investigations or medication changes. Geriatricians entered their main findings and recommendations onto a standard template.
In total, 687 recommendations for changes in patients' medication regimens were made for 169 (91%) patients. In 17 (9%) patients there was no recommendation to alter medications. This resulted in an average of four alterations in medication per patient. The predominant changes to medications were to stop medications (34%) or to reduce the dosage (24%). Starting a new medication represented 18% of all the medication changes. Adherence rates to geriatrician medication recommendations were 72% at 6 months and 65% at 12 months.
CGA of older patients with complex needs, by geriatricians in a general practice care setting, is feasible. Our study demonstrated constructive collaboration between GPs and geriatricians from secondary care, suggesting further studies and clinical trials are feasible and have scope to yield beneficial outcomes.
评估通过综合老年评估(CGA)对患有多种疾病的虚弱患者进行药物优化的可行性和潜在临床获益,方法:在斯托克顿的一个地区的七家全科医生(GP)诊所自愿参加。全科医生选择了(n=186)当地永久居民,年龄至少 65 岁,每天服用八种或更多药物的患者。向患者发送了一份书面邀请,概述了评估目的/格式。在对患者进行评估之前,初级保健人员准备了详细说明患者病史,最近的咨询,当前药物,最近的实验室检查和社会情况的详细信息。每位患者分配一小时的 CGA,由三位老年病医生中的一位进行,以确保有足够的时间探讨所有相关方面。评估包括全面的病史,详细的临床检查,平衡和移动能力评估,精神功能以及家庭环境和支持安排的信息。咨询后,老年病医生就进一步评估,检查或药物更改提出建议。老年病医生将他们的主要发现和建议输入到标准模板中。结果:总共为 169 名(91%)患者的患者药物治疗方案做出了 687 项更改建议。在 17 名(9%)患者中,没有建议改变药物。这导致每位患者平均改变四种药物。药物的主要变化是停止用药(34%)或减少剂量(24%)。开始新的药物占所有药物变化的 18%。在 6 个月时,老年病医生对药物建议的依从率为 72%,在 12 个月时为 65%。结论:在一般实践护理环境中,由老年病医生对有复杂需求的老年患者进行 CGA 是可行的。我们的研究表明,二级保健中的全科医生和老年病医生之间进行了建设性的合作,这表明进一步的研究和临床试验是可行的,并且有可能产生有益的结果。