Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100, Sassari, Italy.
Respiratory Disease Institute, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 43, 07100, Sassari, Italy.
Neurol Sci. 2018 Jan;39(1):145-147. doi: 10.1007/s10072-017-3134-z. Epub 2017 Sep 30.
It has been reported that during and/or after acute trigeminal nerve stimulation (TNS) a state of sedation, decreased attention and vigilance, with a tendency to fall asleep, occurs. Whether these effects are due to a hypnotic action of TNS is yet to be demonstrated. This pilot study investigates whether acute TNS affects the latency of sleep using the Multiple Sleep Latency Test (MSLT) in healthy subjects. MSLT was performed in 14 healthy subjects after 20 min of real- and a sham-TNS, delivered in two different sessions. Mean latency of sleep across the five naps accorded and the latency of sleep for each nap was determined. All subjects reported a state of relaxation or drowsiness after the real-TNS session. Repeated-measures ANOVA showed no significant differences in sleep latency between the real and sham conditions. The sedative effects of acute TNS do not seem associated to a hypnotic effect.
据报道，在急性三叉神经刺激（TNS）期间和/或之后，会出现镇静、注意力和警觉性下降、倾向于入睡的状态。这些影响是否是由于 TNS 的催眠作用尚待证明。本初步研究旨在通过多睡眠潜伏期测试（MSLT）在健康受试者中调查急性 TNS 是否会影响睡眠潜伏期。在两次不同的治疗中，在 20 分钟的真实和假 TNS 后，对 14 名健康受试者进行了 MSLT。确定了五次小睡的平均睡眠潜伏期和每次小睡的潜伏期。所有受试者在真实 TNS 治疗后报告处于放松或昏昏欲睡的状态。重复测量方差分析显示，真实和假条件之间的睡眠潜伏期没有显著差异。急性 TNS 的镇静作用似乎与催眠作用无关。
