Haratake J, Horie A, Furuta A, Yamato H
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Acta Pathol Jpn. 1988 Jan;38(1):89-93. doi: 10.1111/j.1440-1827.1988.tb01075.x.
A massive hepatic infarction was found in a 44-year-old man who had suffered from polyarteritis nodosa for two years. The polyarteritis had been well controlled by administration of corticosteroids, but he died due to an opportunistic fungal infection. At autopsy, a massive hepatic infarct and a fresh thrombus occluding the right portal vein trunk were found. In addition, occlusion of the heptic arterial branch with fibrosis and dissociation of elastic fibers due to polyarteritis was noted. Massive hepatic infarction is uncommon. The clinicopathologic features of this case are described, and the pathogenesis of hepatic infarcts is discussed.
一名患有结节性多动脉炎两年的44岁男性被发现有大面积肝梗死。多动脉炎通过使用皮质类固醇得到了很好的控制，但他因机会性真菌感染而死亡。尸检时，发现大面积肝梗死和右门静脉主干有新鲜血栓形成。此外，还注意到由于多动脉炎导致肝动脉分支闭塞伴纤维化和弹性纤维分离。大面积肝梗死并不常见。本文描述了该病例的临床病理特征，并讨论了肝梗死的发病机制。
