Ross Justin, Manteghi Alexander, Rethy Kimberly, Ding James, Chennupati Sri Kiran
St. Christopher's Hospital for Children, Philadelphia, PA, United States.
St. Christopher's Hospital for Children, Philadelphia, PA, United States.
Int J Pediatr Otorhinolaryngol. 2017 Oct;101:132-136. doi: 10.1016/j.ijporl.2017.07.033. Epub 2017 Jul 25.
We conducted a retrospective analysis of patients at a tertiary care children's hospital who underwent excision of neck mass with proven TGDC histopathology from 2005 to 2015. Patient demographics and presentation, preoperative workup, surgeon specialty, procedural details, lesion characteristics, and complication rates including recurrence were evaluated.
108 patients (51% male, 49% female), aged 6 months to 20 years (mean 6 years) met inclusion criteria. 121 procedures were performed: 96 (79.3%) for primary disease and 25 (20.7%) for recurrence. 32 patients (27.8%) were infected preoperatively, resulting in a significant increase in complications and recurrence (46.9% and 28.1%, respectively). Lack of preoperative imaging was correlated with increased recurrence (p = 0.0002). Recurrence rate after treatment for primary (11.3%) versus secondary disease (24%) was not significant (p = 0.23). Total recurrence rate differed between ENT (9.1%) and Pediatric Surgery (PS) (27.3%) (p = 0.0172). Difference was not significant for recurrence in primary disease (10% ENT, 14.8% PS, p = 0.49), but was for secondary disease (5.6% ENT, 71.4% PS, p = 0.002). Modifications of Sistrunk's procedure did not result in increased rates of recurrence (p = 0.1273).
Preoperative TGDC infection and lack of imaging led to a significant increase in postoperative complications, including recurrence. Surgical specialty significantly affected recurrence rates following excision overall and in secondary disease. Recurrence was not affected by surgical technique, age, sex, cyst size, or mucin rich histology.
我们对一家三级儿童专科医院2005年至2015年期间接受颈部肿块切除术且组织病理学证实为TGDC的患者进行了回顾性分析。评估了患者的人口统计学和临床表现、术前检查、外科医生专业、手术细节、病变特征以及包括复发在内的并发症发生率。
108例患者(男性51%,女性49%),年龄6个月至20岁(平均6岁)符合纳入标准。共进行了121例手术:96例(79.3%)为原发性疾病,25例(20.7%)为复发性疾病。32例患者(27.8%)术前感染,导致并发症和复发率显著增加(分别为46.9%和28.1%)。术前未进行影像学检查与复发率增加相关(p = 0.0002)。原发性疾病治疗后的复发率(11.3%)与继发性疾病(24%)相比无显著差异(p = 0.23)。耳鼻喉科(ENT)和小儿外科(PS)的总复发率不同(分别为9.1%和27.3%)(p = 0.0172)。原发性疾病复发率差异不显著(ENT为10%,PS为14.8%,p = 0.49),但继发性疾病差异显著(ENT为5.6%,PS为71.4%,p = 0.002)。Sistrunk手术的改良并未导致复发率增加(p = 0.1273)。
术前TGDC感染和未进行影像学检查导致术后并发症显著增加,包括复发。外科专业显著影响总体切除术后和继发性疾病的复发率。复发不受手术技术、年龄、性别、囊肿大小或富含黏液组织学的影响。