Ogwulu Chidubem B, Jackson Louise J, Kinghorn Philip, Roberts Tracy E
Health Economics Unit, School of Health and Population Sciences, University of Birmingham, Birmingham, UK.
Health Economics Unit, School of Health and Population Sciences, University of Birmingham, Birmingham, UK.
Value Health. 2017 Sep;20(8):1180-1197. doi: 10.1016/j.jval.2017.03.009. Epub 2017 May 12.
A broad literature on health state utility values exists, but compared with chronic health states (HSs), issues surrounding the valuation of temporary health states (THSs) have been poorly explored.
To assess the methods used by previous studies to value HSs that are considered temporary so as to determine the strengths and limitations associated with various approaches and to inform future study designs.
A systematic review was undertaken to explore the methods used, assess how the valuation was conducted for diseases that might lead to HSs deemed as temporary, and identify the challenges encountered in the valuation of THSs.
Of the 36 relevant studies, 22 were explicit that the HS being valued was temporary. Most of the studies used more than one technique (often incorporating both conventional and adapted approaches). In using adapted techniques, the primary challenge was identifying an appropriate intermediate "anchor" HS and the possibility of negative utilities.
There is no agreement on the most methodologically robust approach to THS valuation. Valuation is complex and important issues relating to the validity, practicality, and reliability of the techniques used were not adequately covered by most of the studies identified.
关于健康状态效用值存在大量文献,但与慢性健康状态相比,围绕临时健康状态估值的问题研究较少。
评估以往研究用于评估被视为临时的健康状态的方法,以确定各种方法的优缺点,并为未来的研究设计提供参考。
进行了一项系统综述,以探讨所使用的方法,评估对可能导致被视为临时的健康状态的疾病如何进行估值,并确定在临时健康状态估值中遇到的挑战。
在36项相关研究中,22项明确指出所评估的健康状态是临时的。大多数研究使用了不止一种技术(通常同时采用传统方法和改良方法)。在使用改良技术时,主要挑战是确定合适的中间“锚定”健康状态以及出现负效用的可能性。
对于临时健康状态估值,在方法学上最稳健的方法尚无定论。估值很复杂,大多数已确定的研究未充分涵盖与所使用技术的有效性、实用性和可靠性相关的重要问题。