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社会剥夺对英格兰髋部骨折发病率的影响 14 年来并未改变:对英国医院住院统计数据(2001-2015 年)的分析。

The effect of social deprivation on hip fracture incidence in England has not changed over 14 years: an analysis of the English Hospital Episodes Statistics (2001-2015).

机构信息

Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Learning & Research Building (Level 1), Southmead Hospital, Bristol, BS10 5NB, UK.

Nuffield Trust, London, UK.

出版信息

Osteoporos Int. 2018 Jan;29(1):115-124. doi: 10.1007/s00198-017-4238-2. Epub 2017 Sep 30.

Abstract

UNLABELLED

Deprivation predicts increased hip fracture risk. Over 14 years, hip fracture incidence increased among men with persisting inequalities. Among women, inequalities in incidence were less pronounced; whilst incidence decreased overall, this improvement was seen marginally less in women from the most deprived areas. Hip fracture prevention programmes have not reduced inequalities.

PURPOSE

Deprivation is associated with increased hip fracture risk. We examined the effect of area-level deprivation on hip fracture incidence in England over 14 years to determine whether inequalities have changed over time.

METHODS

We used English Hospital Episodes Statistics (2001/2002-2014/2015) to identify hip fractures in adults aged 50+ years and mid-year population estimates (2001-2014) from the Office for National Statistics. The Index of Multiple Deprivation measured local area deprivation. We calculated age-adjusted incidence rate ratios (IRR) for hip fracture, stratified by gender and deprivation quintiles.

RESULTS

Over 14 years, we identified 747,369 hospital admissions with an index hip fracture; the number increased from 50,640 in 2001 to 55,092 in 2014; the proportion of men increased from 22.2% to 29.6%. Whereas incidence rates decreased in women (annual reduction 1.1%), they increased in men (annual increase 0.6%) (interaction p < 0.001). Incidence was higher in more deprived areas, particularly among men: IRR most vs. least deprived quintile 1.50 [95% CI 1.48, 1.52] in men, 1.17 [1.16, 1.18] in women. Age-standardised incidence increased for men across all deprivation quintiles from 2001 to 2014. Among women, incidence fell more among those least compared to most deprived (year by deprivation interaction p < 0.001).

CONCLUSIONS

Deprivation is a stronger relative predictor of hip fracture incidence in men than in women. However, given their higher hip fracture incidence, the absolute burden of deprivation on hip fractures is greater in women. Despite public health efforts to prevent hip fractures, the health inequality gap for hip fracture incidence has not narrowed for men, and marginally widened among women.

摘要

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剥夺与髋部骨折风险增加相关。在超过 14 年的时间里,持续存在的不平等现象导致男性髋部骨折发病率上升。而女性的发病率不平等程度则不太明显;虽然总体发病率下降,但在最贫困地区的女性中,这一改善幅度略小。髋部骨折预防计划并未减少不平等现象。

目的

剥夺与髋部骨折风险增加相关。我们研究了英格兰在 14 年时间内的地区贫困程度对髋部骨折发病率的影响,以确定不平等现象是否随时间而变化。

方法

我们使用英国医院住院统计数据(2001/2002 年至 2014/2015 年)确定了 50 岁及以上成年人的髋部骨折病例,并从英国国家统计局(Office for National Statistics)获取了 2001 年至 2014 年的中年人口估计数。多因素剥夺指数(Index of Multiple Deprivation)衡量了当地的贫困程度。我们按性别和贫困五分位数对髋部骨折的年龄调整发病率比(incidence rate ratio,IRR)进行了分层计算。

结果

在 14 年期间,我们共确定了 747369 例髋部骨折住院病例;病例数量从 2001 年的 50640 例增加到 2014 年的 55092 例;男性的比例从 22.2%增加到 29.6%。女性的发病率呈下降趋势(年下降 1.1%),而男性的发病率呈上升趋势(年上升 0.6%)(交互作用 p < 0.001)。在更贫困的地区,发病率更高,尤其是男性:与最贫困的五分位数相比,发病率最高的五分位数为 1.50 [95%可信区间(CI)1.48,1.52],女性为 1.17 [1.16,1.18]。2001 年至 2014 年,所有贫困五分位数的男性年龄标准化发病率均有所上升。在女性中,与最贫困的五分位数相比,发病率下降幅度最大(按贫困程度分层的年份交互作用 p < 0.001)。

结论

与女性相比,剥夺是男性髋部骨折发病率的一个更强的相对预测因素。然而,由于男性髋部骨折的发病率较高,因此女性在髋部骨折方面的贫困负担绝对更大。尽管公共卫生部门努力预防髋部骨折,但男性髋部骨折发病率的健康不平等差距并未缩小,女性的差距则略有扩大。

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