Edriss Hawa, Kelley John, Demke Joshua
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.
Proc (Bayl Univ Med Cent). 2017 Oct;30(4):452-454. doi: 10.1080/08998280.2017.11930226.
Sarcoidosis is a chronic granulomatous inflammation of uncertain etiology that can involve any organ system in the body. Sinonasal and laryngeal involvement is rare, poorly understood, and difficult to diagnose. Additionally, the extent of the disease is variable, and the response to systemic corticosteroids is often poor. We report a case of a 55-year-old woman with prior cutaneous sarcoidosis who presented with chronic nasal congestion, difficulty breathing, dysphonia, and stridor, and biopsy of the nasal vestibule revealed noncaseating granulomatous inflammation.
结节病是一种病因不明的慢性肉芽肿性炎症，可累及身体的任何器官系统。鼻窦和喉部受累罕见，了解甚少且难以诊断。此外，疾病范围可变，对全身性皮质类固醇的反应通常较差。我们报告一例55岁女性，既往有皮肤结节病，出现慢性鼻塞、呼吸困难、声音嘶哑和喘鸣，鼻前庭活检显示非干酪样肉芽肿性炎症。
