LAQV-REQUIMTE, Department of Chemistry, Faculty of Science and Technology, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
NOVA LINCS, Department of Computer Science, Faculty of Science and Technology, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
Bioinformatics. 2018 Jan 1;34(1):120-121. doi: 10.1093/bioinformatics/btx556.
The representation of metabolic reactions strongly relies on visualization, which is a major barrier for blind users. The NavMol software renders the communication and interpretation of molecular structures and reactions accessible by integrating chemoinformatics and assistive technology. NavMol 3.0 provides a molecular editor for metabolic reactions. The user can start with templates of reactions and build from such cores. Atom-to-atom mapping enables changes in the reactants to be reflected in the products (and vice-versa) and the reaction centres to be automatically identified. Blind users can easily interact with the software using the keyboard and text-to-speech technology.
NavMol 3.0 is free and open source under the GNU general public license (GPLv3), and can be downloaded at http://sourceforge.net/projects/navmol as a JAR file.
代谢反应的表示强烈依赖于可视化，这对于盲人用户来说是一个主要的障碍。NavMol 软件通过整合化学生信学和辅助技术，使分子结构和反应的交流和解释变得可访问。NavMol 3.0 为代谢反应提供了一个分子编辑器。用户可以从反应模板开始，并从这些核心构建。原子到原子的映射使反应物中的变化反映在产物中（反之亦然），并且自动识别反应中心。盲人用户可以使用键盘和文本到语音技术轻松与软件交互。
NavMol 3.0 是免费的，根据 GNU 通用公共许可证 (GPLv3) 开源，可以从 http://sourceforge.net/projects/navmol 作为 JAR 文件下载。
