Anuhya T V, Acharya Raviraj, MadhyasthaA Sharath, Bhat Ram, Nayak Veena
Postgraduate, Department of Pharmacology, KMC, Manipal University, Udupi, Karnataka, India.
Professor, Department of Medicine, KMC, Manipal University, Udupi, Karnataka, India.
J Clin Diagn Res. 2017 Aug;11(8):OD05-OD06. doi: 10.7860/JCDR/2017/27584.10387. Epub 2017 Aug 1.
Meropenam, a beta-lactam antibiotic has been used for severe infections of skin, tissue, intra- abdominal and urogenital infections in hospitalized patients. The common adverse effects reported are diarrhoea, vomiting, rashes and hypersensitivity reactions. Here we report two cases of meropenam induced hypokalemia, wherein, meropenam was prescribed for cellulitis and urinary tract infection in the first and second case respectively. Hypokalemia can manifest as muscular weakness, fatigue, muscle cramps, constipation, ileus, flaccid paralysis, hyporeflexia, hypercapnia, tetany, rhabdomyolysis or respiratory failure. Hence, it is necessary to make physicians aware of such an adverse effect which can develop with meropenam.
