Baiju R M, Peter Elbe, Varghese N O, Anju P
Associate Professor, Department of Periodontics, Government Dental College Thrissur, Kerala University of Health Sciences, Kerala, India.
Associate Professor, Department of Orthodontics, Government Dental College Alleppey, Kerala University of Health Sciences, Kerala, India.
J Clin Diagn Res. 2017 Aug;11(8):ZC14-ZC19. doi: 10.7860/JCDR/2017/28505.10343. Epub 2017 Aug 1.
Patient Reported Outcomes (PROs) are now regarded as a fundamental measure of therapeutic success. Patient's opinion regarding the impact of disease and its treatment is assessed using scales such as Oral Health Related Quality Of Life (OHRQoL) tools. Patient centred outcome assessment is now being considered as a primary outcome measure in clinical trials.
To evaluate whether treatment of periodontal disease could influence OHRQoL based on available literature.
An electronic search was done in Google, Google Scholar and Pubmed for articles in English language using the terms Quality of Life or ORHQoL or PROs or patient centered outcome and periodontal therapy. The search commenced on 1 September 2016 and ended on 15 December 2016. Studies that employed one or more than one multi-item OHRQoL instrument to assess PROs related to either non-surgical or surgical periodontal therapy were reviewed.
Initially 423 relevant articles were obtained, from which based on screening titles and abstracts 396 were excluded. Full text of remaining 27 articles were retrieved. Nineteen clinical studies with 1345 participants and 2 systematic reviews were included after the full text review.
Both surgical and Non-surgical Periodontal Therapy (NSPT) significantly influenced the OHRQoL scores. However the change in scores after surgical therapy when compared to nonsurgical therapy was not statistically significant. There is a need for a specific PROs scale that could potentially tap the entire dimension of the change in patients' perception brought about by periodontal therapy.
患者报告结局(PROs)现在被视为治疗成功的一项基本指标。使用诸如口腔健康相关生活质量(OHRQoL)工具等量表来评估患者对疾病及其治疗影响的看法。以患者为中心的结局评估现在正被视为临床试验中的主要结局指标。
根据现有文献评估牙周疾病的治疗是否会影响口腔健康相关生活质量。
在谷歌、谷歌学术和PubMed上进行电子检索,使用生活质量、OHRQoL、PROs或以患者为中心的结局以及牙周治疗等术语搜索英文文章。检索于2016年9月1日开始,2016年12月15日结束。对采用一种或多种多项目OHRQoL工具来评估与非手术或手术牙周治疗相关的PROs的研究进行了综述。
最初获得了423篇相关文章,基于标题和摘要筛选后排除了396篇。检索到其余27篇文章的全文。全文综述后纳入了19项有1345名参与者的临床研究和2项系统评价。
手术和非手术牙周治疗(NSPT)均显著影响OHRQoL评分。然而,与非手术治疗相比,手术治疗后评分的变化在统计学上并不显著。需要一种特定的PROs量表,它有可能全面反映牙周治疗给患者认知带来的变化。