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非手术牙周治疗对口腔健康相关生活质量的影响:系统评价和荟萃分析。

The impact of nonsurgical periodontal treatment on oral health-related quality of life: a systematic review and meta-analysis.

机构信息

Periodontology Department, Egas Moniz Dental Clinic, Egas Moniz, CRL, Monte de Caparica, Portugal.

Clinical Research Unit (CRU), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Egas Moniz, CRL, Monte de Caparica, Portugal.

出版信息

Clin Oral Investig. 2020 Feb;24(2):585-596. doi: 10.1007/s00784-019-03188-1. Epub 2020 Jan 4.

DOI:10.1007/s00784-019-03188-1
PMID:31901977
Abstract

OBJECTIVE

To estimate the impact of nonsurgical periodontal treatment (NSPT) on patients' oral health-related quality of life (OHRQoL). The focused question for this systematic review was: in adults patients with periodontitis, does NSPT improve oral health-related quality of life?

MATERIAL AND METHODS

Five databases (PubMed, CIHNL, EMBASE, LILACS and CENTRAL) were searched up to April 2019 (PROSPERO CRD42018103393). Intervention trials and cohort studies assessing the OHRQoL data of adults with periodontitis, enduring non-surgical periodontal treatment (NSPT) were eligible for inclusion. Subgroup random-effects meta-analysis was conducted methodically.

RESULTS

Overall, 491 studies were retrieved, out of which 19 met the inclusion criteria. Two randomized clinical trials (RCTs) and ten cohort studies were further analysed. Seven cohort studies were included in the statistical analysis. Subgroup meta-analyses of cohort studies revealed that NSPT improves in average 2.49 (95% CI 0.95-4.02), 8.94 (95% CI 6.89-10.99) and 6.49 (95% CI 5.11-7.88) OHRQoL levels at 1-2 weeks, 3-4 weeks and 6-12 weeks of post-treatment, respectively.

CONCLUSIONS

NSPT procedures greatly improve the oral health-related quality of life within a short time, remaining stable after 3 months of treatment.

CLINICAL RELEVANCE

This systematic review brings forward summary evidence that NSPT improves the OHRQoL in adults with periodontitis from a patient-centred perception and remain stable in the short term.

摘要

目的

评估非手术性牙周治疗(NSPT)对患者口腔健康相关生活质量(OHRQoL)的影响。本系统评价的重点问题是:在患有牙周炎的成年患者中,NSPT 是否能改善口腔健康相关生活质量?

材料和方法

检索了 5 个数据库(PubMed、CIHNL、EMBASE、LILACS 和 CENTRAL),检索时间截至 2019 年 4 月(PROSPERO CRD42018103393)。纳入评估成人牙周炎患者 OHRQoL 数据并接受非手术性牙周治疗(NSPT)的干预试验和队列研究。采用系统方法进行亚组随机效应荟萃分析。

结果

共检索到 491 项研究,其中 19 项符合纳入标准。进一步分析了 2 项随机临床试验(RCT)和 10 项队列研究。有 7 项队列研究纳入了统计分析。队列研究的亚组荟萃分析显示,NSPT 在治疗后 1-2 周、3-4 周和 6-12 周,平均分别改善 2.49(95%CI 0.95-4.02)、8.94(95%CI 6.89-10.99)和 6.49(95%CI 5.11-7.88)的 OHRQoL 水平。

结论

NSPT 程序在短时间内大大改善了口腔健康相关生活质量,在治疗 3 个月后保持稳定。

临床意义

本系统评价提供了综合证据,表明 NSPT 从患者为中心的角度改善了成人牙周炎患者的 OHRQoL,并且在短期内保持稳定。

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Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.
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Changes in Osseous Morphology Following Non-Surgical Periodontal Therapy: A Possible Paradigm Shift for the Treatment of Intrabony Defects?非手术牙周治疗后骨形态的变化:治疗骨内缺损的一种可能的范式转变?
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Pathogenic mechanisms and potential applications of extracellular vesicles from periodontal pathogens in periodontitis.牙周病原体来源的细胞外囊泡在牙周炎中的致病机制及潜在应用
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