Gozen Ali Serdar, Akin Yigit, Ates Mutlu, Fiedler Marcel, Rassweiler Jens
Department of Urology, SLK-Klinikum Heilbronn, University of Heidelberg, Heilbronn.
Arch Ital Urol Androl. 2017 Oct 3;89(3):186-191. doi: 10.4081/aiua.2017.3.186.
To evaluate the effects of bladder neck reconstruction techniques on early continence after laparoscopic radical prostatectomy (LRP).
This non-randomized retrospective study analyzed prospectively collected data concerning LRP. In total, 3107 patients underwent LRP between March 1999 and December 2016. Exclusion criteria were preoperative urinary incontinence, previous history of external beam radiotherapy, co-morbities which may affect urinary continence such as diabetes mellitus and/or neurogenic disorders, irregular followup, and follow-up shorter than 24 months. All patients were divided into one of three groups, posterior reconstruction being performed in Group 1 (n = 112), anterior reconstruction in Group 2 (n = 762), and bladder neck sparing (BNS) in Group 3 (n = 987). Demographic and pre-, peri-, and postoperative data were collected. Multivariate analyses were performed to determine factors affecting early continence after LRP.
1861 patients were enrolled in the study. The mean follow-up period was 48.12 ± 29.8 months, and subjects' mean age was 63.6 ± 6.2 years. There was no significant difference among the groups in terms of demographic or preoperative data. Postoperative data, including oncological outcomes, were similar among the groups. The level of early continence was higher in Group 3 than in the other groups (p < 0.001). Multivariate analyses identified BNS and age as parameters significantly affecting early continence levels after LRP (p < 0.001 and p < 0.001, respectively). Bladder neck reconstruction provided less earlier continence than BNS.
评估膀胱颈重建技术对腹腔镜根治性前列腺切除术(LRP)后早期控尿的影响。
本非随机回顾性研究分析了前瞻性收集的有关LRP的数据。1999年3月至2016年12月期间,共有3107例患者接受了LRP。排除标准包括术前尿失禁、既往体外束放射治疗史、可能影响尿控的合并症(如糖尿病和/或神经源性疾病)、随访不规律以及随访时间短于24个月。所有患者被分为三组之一,第1组(n = 112)进行后重建,第2组(n = 762)进行前重建,第3组(n = 987)进行膀胱颈保留(BNS)。收集了人口统计学数据以及术前、术中和术后数据。进行多变量分析以确定影响LRP后早期控尿的因素。
1861例患者纳入研究。平均随访期为48.12±29.8个月,受试者平均年龄为63.6±6.2岁。各组之间在人口统计学或术前数据方面无显著差异。包括肿瘤学结果在内的术后数据在各组之间相似。第3组的早期控尿水平高于其他组(p<0.001)。多变量分析确定BNS和年龄是显著影响LRP后早期控尿水平的参数(分别为p<0.001和p<0.001)。膀胱颈重建提供的早期控尿效果不如BNS。