Maged Ahmed, Youssef Gamal, Hussien Amal, Gaafar Hassan, Elsherbini Moutaz, Elkomy Rasha, Eid Marwa, Abd El-Hamid Nermeen, Abdel-Razek Abdel-Rahman
a Department of Obstetrics and Gynecology , Cairo University , Cairo , Egypt.
b Pediatrics Department , Cairo University , Cairo , Egypt.
J Matern Fetal Neonatal Med. 2019 Feb;32(4):660-665. doi: 10.1080/14767058.2017.1387898. Epub 2017 Oct 12.
Respiratory distress is commonly encountered among premature babies immediately after birth resulting in significant neonatal morbidity or mortality.
To evaluate the possible correlation between three dimensional fetal lung volumes (FLVs) and neonatal respiratory outcomes.
A cohort study included 100 pregnant women who participated in the study and were divided into two groups; group A (n: 50 - women pregnant ±34-37 weeks) and group B (n: 50 - women pregnant ±37 to 40 weeks). A three dimensional measurement of the right fetal lung was made using virtual organ computer-aided analysis (VOCAL) software then correlated to neonatal respiratory functions namely Apgar score at birth and the occurrence of respiratory distress syndrome (RDS).
In group A, FLV was negatively correlated with Apgar score and the occurrence of RDS. In group B, FLV showed no statistical correlation with Apgar score and the occurrence of RDS.
Three dimensional fetal lung volumes might be an accurate noninvasive predictor for the development of RDS among preterm fetuses.
呼吸窘迫在早产儿出生后立即常见，会导致显著的新生儿发病或死亡。
评估三维胎儿肺容积（FLV）与新生儿呼吸结局之间的可能相关性。
一项队列研究纳入了100名参与研究的孕妇，并将其分为两组；A组（n：50 - 怀孕±34 - 37周的女性）和B组（n：50 - 怀孕±37至40周的女性）。使用虚拟器官计算机辅助分析（VOCAL）软件对胎儿右肺进行三维测量，然后将其与新生儿呼吸功能即出生时的阿氏评分和呼吸窘迫综合征（RDS）的发生情况相关联。
在A组中，FLV与阿氏评分和RDS的发生呈负相关。在B组中，FLV与阿氏评分和RDS的发生无统计学相关性。
三维胎儿肺容积可能是早产胎儿发生RDS的准确无创预测指标。
