Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Arthroscopy. 2018 Jan;34(1):321-330.e1. doi: 10.1016/j.arthro.2017.07.006. Epub 2017 Sep 29.
The purpose of this systematic literature review focused on hip arthroscopy was to (1) report the venous thromboembolism (VTE) event incidence in patients who receive VTE prophylaxis and those who do not, (2) report how VTE prophylaxis is currently being administered, and (3) report operative and patient-related risk factors for VTE identified in the literature.
The electronic databases MEDLINE, Embase, and PubMed were searched from database inception to October 10, 2016, and screened in duplicate for relevant studies. Data were collected regarding VTE prophylaxis, traction use, surgical time, VTE incidence, patient and operative factors, and postoperative weight bearing and rehabilitation. Study quality was assessed in duplicate with the Methodological Index for Non-Randomized Studies criteria.
Outcome analyses included 14 studies that involved 2,850 patients (2,985 hips). The weighted mean follow-up period was 19 ± 8 months, ranging from 7 days to 103 months. The weighted mean age was 40.7 ± 7 years, ranging from 6 to 82 years, and 39.6% of patients were male patients. The overall weighted proportion of VTE events after hip arthroscopy found in 14 included studies was 2.0% (95% confidence interval, 0.01%-4.1%), with 25 VTE events. Several studies reported patient risk factors, which included increased age, increased body mass index, prolonged traction time, and use of oral contraceptives.
The use and efficacy of VTE prophylaxis are highly under-reported within hip arthroscopy. The low incidence of VTE events found in this review (2.0%) suggests that prophylaxis may not be necessary in low-risk patients undergoing hip arthroscopy; however, the true rate may be under-reported. Current literature suggests that prophylaxis is typically not prescribed. Early mobility and postoperative rehabilitation may also help to further mitigate the risk of VTE events, but use of these strategies needs further prospective evaluation.
Level IV, systematic review of Level II through IV studies.
本次髋关节镜检查系统文献回顾的目的是:(1)报告接受静脉血栓栓塞(VTE)预防和未接受预防的患者的 VTE 事件发生率;(2)报告目前 VTE 预防的实施情况;(3)报告文献中确定的与手术和患者相关的 VTE 危险因素。
从数据库建立到 2016 年 10 月 10 日,对 MEDLINE、Embase 和 PubMed 电子数据库进行了检索,并进行了重复筛选,以寻找相关研究。收集了有关 VTE 预防、牵引使用、手术时间、VTE 发生率、患者和手术因素以及术后负重和康复的资料。采用非随机研究方法学指数对研究质量进行了重复评估。
对纳入的 14 项研究进行了结局分析,共纳入 2850 例患者(2985 髋)。加权平均随访时间为 19 ± 8 个月,范围为 7 天至 103 个月。加权平均年龄为 40.7 ± 7 岁,范围为 6 岁至 82 岁,39.6%的患者为男性。14 项纳入研究中,髋关节镜检查后 VTE 事件的总体加权发生率为 2.0%(95%置信区间,0.01%-4.1%),共发生 25 例 VTE 事件。一些研究报告了患者危险因素,包括年龄增加、体重指数增加、牵引时间延长和使用避孕药。
髋关节镜检查中,VTE 预防的使用和效果报告严重不足。本综述发现 VTE 事件的发生率较低(2.0%),这表明在接受髋关节镜检查的低风险患者中,预防可能不是必需的;但是,实际发生率可能被低估了。目前的文献表明,通常不建议预防性使用抗凝药物。早期活动和术后康复也可能有助于进一步降低 VTE 事件的风险,但这些策略的使用需要进一步前瞻性评估。
IV 级,对 II 级至 IV 级研究的系统评价。