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Int J Cardiol Congenit Heart Dis. 2022 Mar 28;8:100366. doi: 10.1016/j.ijcchd.2022.100366. eCollection 2022 Jun.

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1
Postcardiotomy ECMO Support after High-risk Operations in Adult Congenital Heart Disease.成人先天性心脏病高危手术后的心内直视术后体外膜肺氧合支持
Congenit Heart Dis. 2016 Dec;11(6):751-755. doi: 10.1111/chd.12396. Epub 2016 Jul 20.
2
Health status and quality of life of survivors of extra corporeal membrane oxygenation: a cross-sectional study.体外膜肺氧合幸存者的健康状况和生活质量:一项横断面研究。
J Adv Nurs. 2016 Jul;72(7):1626-37. doi: 10.1111/jan.12943. Epub 2016 Feb 23.
3
Problems and health needs of adult extracorporeal membrane oxygenation patients following hospital discharge: A qualitative study.成人体外膜肺氧合患者出院后的问题与健康需求:一项定性研究。
Heart Lung. 2016 Mar-Apr;45(2):147-53. doi: 10.1016/j.hrtlng.2015.12.005. Epub 2016 Feb 4.
4
Nationwide Hospitalization Trends in Adult Congenital Heart Disease Across 2003-2012.2003年至2012年全国成人先天性心脏病的住院趋势
J Am Heart Assoc. 2016 Jan 19;5(1):e002330. doi: 10.1161/JAHA.115.002330.
5
Contemporary survival of adults with congenital heart disease.成人先天性心脏病的当代生存率。
Heart. 2015 Dec;101(24):1989-95. doi: 10.1136/heartjnl-2015-308144. Epub 2015 Nov 5.
6
Projected growth of the adult congenital heart disease population in the United States to 2050: an integrative systems modeling approach.美国成年先天性心脏病患者数量到2050年的预计增长:一种综合系统建模方法。
Popul Health Metr. 2015 Oct 15;13:29. doi: 10.1186/s12963-015-0063-z. eCollection 2015.
7
Survival and quality of life after extracorporeal life support for refractory cardiac arrest: A case series.体外生命支持治疗难治性心脏骤停后的生存和生活质量:病例系列。
J Thorac Cardiovasc Surg. 2015 Oct;150(4):947-54. doi: 10.1016/j.jtcvs.2015.05.070. Epub 2015 Jun 5.
8
Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score.预测 ECMO 治疗难治性心源性休克后的生存率:静脉-动脉-体外膜肺氧合(VA-ECMO)后生存率评分(SAVE 评分)。
Eur Heart J. 2015 Sep 1;36(33):2246-56. doi: 10.1093/eurheartj/ehv194. Epub 2015 Jun 1.
9
Trends in utilization of specialty care centers in California for adults with congenital heart disease.加利福尼亚州先天性心脏病成人专科护理中心的使用趋势。
Am J Cardiol. 2015 May 1;115(9):1298-304. doi: 10.1016/j.amjcard.2015.02.013. Epub 2015 Feb 12.
10
Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010.2000 年至 2010 年普通人群中心脏病的终生患病率。
Circulation. 2014 Aug 26;130(9):749-56. doi: 10.1161/CIRCULATIONAHA.113.008396. Epub 2014 Jun 18.

先天性心脏病手术成年患者体外膜肺氧合的需求:应用的影响与趋势

The Need for Extracorporeal Membrane Oxygenation in Adults Undergoing Congenital Heart Surgery: Impact and Trends of Utilization.

作者信息

Aiello Salvatore, Loomba Rohit S, Kriz Connor, Buelow Matthew, Aggarwal Saurabh, Arora Rohit R

机构信息

Division of Cardiology, Chicago Medical School, North Chicago, IL, USA.

Division of Cardiology, Children's Hospital of Wisconsin/Medical College of Wisconsin, Milwaukee, WI, USA.

出版信息

Indian J Crit Care Med. 2017 Sep;21(9):547-551. doi: 10.4103/ijccm.IJCCM_169_17.

DOI:10.4103/ijccm.IJCCM_169_17
PMID:28970652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5613604/
Abstract

INTRODUCTION

Adults with congenital heart disease (ACHD) represent a population with unique health-care needs. Many patients require cardiac surgery, with some requiring postoperative extracorporeal membrane oxygenation (ECMO). This study aimed to identify the risk factors for the need of postoperative ECMO and characterize the impact of ECMO on admission characteristics.

METHODS

Data from the 2005-2012 iterations of the Nationwide Inpatient Sample were used. ACHD admissions over 18 years with a documented cardiac surgery were included. Univariate analysis was conducted to compare the characteristics between those requiring ECMO and those who did not. Regression analysis was done to identify the independent risk factors associated with ECMO and to determine the impact of ECMO on length, cost, and mortality of the admission.

RESULTS

A total of 186,829 admissions were included. Of these, 446 (0.2%) admissions required ECMO. Those with acute kidney injury, double-outlet right ventricle, or total anomalous pulmonary venous connection were more likely to require ECMO. ECMO was also significantly more utilized in patients undergoing septal defect repair, complete repair of tetralogy of Fallot, atrial switch, and heart transplant. The use of ECMO significantly increased length, cost, and mortality of stay. Overall mortality was 62.6% in the ECMO group.

CONCLUSION

ECMO is only needed in a small proportion of postoperative ACHD patients. The use of ECMO significantly increases cost, length of stay and mortality in these patients. Improved identification of postoperative ACHD patients who are more likely to survive ECMO may facilitate improved survival and decreased resource utilization.

摘要

引言

患有先天性心脏病的成年人(ACHD)是一个有独特医疗需求的群体。许多患者需要进行心脏手术,部分患者术后还需要体外膜肺氧合(ECMO)。本研究旨在确定术后需要ECMO的风险因素,并描述ECMO对入院特征的影响。

方法

使用2005 - 2012年全国住院患者样本的数据。纳入18岁以上有心脏手术记录的ACHD住院患者。进行单因素分析以比较需要ECMO的患者和不需要ECMO的患者的特征。进行回归分析以确定与ECMO相关的独立风险因素,并确定ECMO对住院时间、费用和死亡率的影响。

结果

共纳入186,829例住院患者。其中,446例(0.2%)住院患者需要ECMO。患有急性肾损伤、右心室双出口或完全性肺静脉异位连接的患者更有可能需要ECMO。在进行室间隔缺损修复、法洛四联症完全修复、心房调转术和心脏移植的患者中,ECMO的使用也显著更多。ECMO的使用显著增加了住院时间、费用和死亡率。ECMO组的总体死亡率为62.6%。

结论

只有一小部分ACHD术后患者需要ECMO。ECMO的使用显著增加了这些患者的费用、住院时间和死亡率。更好地识别更有可能在ECMO治疗后存活的ACHD术后患者,可能有助于提高生存率并减少资源利用。