Maria Arti, Agarwal Sheetal, Sharma Anu
Department of Neonatology, PGIMER and RML Hospital, New Delhi, India.
Department of Pediatrics, PGIMER and RML Hospital, New Delhi, India.
Asian J Transfus Sci. 2017 Jul-Dec;11(2):203-205. doi: 10.4103/ajts.AJTS_120_16.
Transfusion-related acute lung injury (TRALI) is a potentially life-threatening complication of blood component transfusion. It is relatively underdiagnosed entity in neonates with scant literature. We report a case of TRALI in a preterm neonate developing acute respiratory distress within 6 h of blood product transfusion in the absence of preexisting lung disease. Prompt ventilator and supportive management were instituted. The baby showed clinical and radiological improvement within 12 h; however, he succumbed to death due to acute massive pulmonary hemorrhage 36 h later. Possibility of TRALI should be kept if there is sudden deterioration of lung function after blood transfusion.
输血相关急性肺损伤（TRALI）是血液成分输血的一种潜在危及生命的并发症。在新生儿中，它是一个相对诊断不足的疾病实体，相关文献较少。我们报告一例早产新生儿发生TRALI的病例，该患儿在输注血液制品后6小时内出现急性呼吸窘迫，且无既往肺部疾病史。立即给予机械通气及支持治疗。患儿在12小时内临床和影像学表现有所改善；然而，36小时后，他因急性大量肺出血死亡。如果输血后肺功能突然恶化，应考虑TRALI的可能性。
