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胸腔内脾组织植入:病史是关键。

Thoracic splenosis: History is the key.

作者信息

Ferrer Marrero Tirsa M, Prieto-Centurion Valentin, Jaffe Howard A

机构信息

Medical College of Wisconsin, Milwaukee, WI, United States.

University of Illinois at Chicago, Chicago, IL, United States.

出版信息

Respir Med Case Rep. 2017 Sep 18;22:251-253. doi: 10.1016/j.rmcr.2017.09.006. eCollection 2017.

DOI:10.1016/j.rmcr.2017.09.006
PMID:28971001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5612806/
Abstract

Splenosis is an acquired ectopic autotransplantation of splenic tissue; that occurs after traumatic splenic rupture and splenectomy [1]. Splenosis is a rare but benign disease, and the diagnosis can be challenging as the multiple incidentally found nodules could mimic malignancy [2]. Abdominopelvic Splenosis is thought to occur in as many as 65% of cases of splenic rupture [1]. However, Thoracic Splenosis is rare and usually involve the left parietal and visceral pleura [1,2]. Intraparenchymal lesions are less common but have been reported in cases of parenchymal and diaphragm laceration [1,2]. Taking a thorough history is of utmost importance, as these patients usually present more than two decades after the splenic traumatic rupture. The use of commonly available nuclear studies will further confirm the diagnosis [3]. This will help to avoid unnecessary procedures, like biopsies; and prevent the potential complications. We present a case of Thoracic Splenosis that highlights the importance of taking a detailed history; and the importance of using nuclear studies for the diagnosis. Further adding to its uniqueness, this case showed with multiple intraparenchymal nodules which is a less common presentation of Splenosis.

摘要

脾组织自体移植是一种后天性的脾组织异位自体移植,发生于外伤性脾破裂和脾切除术后[1]。脾组织自体移植是一种罕见的良性疾病,由于多个偶然发现的结节可能酷似恶性肿瘤,其诊断具有挑战性[2]。据认为,腹腔盆腔脾组织自体移植在脾破裂病例中发生率高达65%[1]。然而,胸腔脾组织自体移植很少见,通常累及左胸膜顶和脏胸膜[1,2]。实质内病变较少见,但在实质和膈肌撕裂病例中已有报道[1,2]。详尽了解病史至关重要,因为这些患者通常在脾外伤性破裂二十多年后才出现症状。使用常用的核医学检查将进一步确诊[3]。这将有助于避免不必要的操作,如活检,并预防潜在的并发症。我们报告一例胸腔脾组织自体移植病例,强调了详尽了解病史的重要性以及使用核医学检查进行诊断的重要性。该病例更独特的是,表现为多个实质内结节,这是脾组织自体移植较少见的表现形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/edc1b485a07e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/09b83a2e5849/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/a712acadf5a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/edc1b485a07e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/09b83a2e5849/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/a712acadf5a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f0/5612806/edc1b485a07e/gr3.jpg

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A Growth Opportunity: Thoracic Splenosis.一个增长机会:胸腔脾组织植入
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2
Thoracic splenosis masquerading as advanced lung cancer.伪装成晚期肺癌的胸腔脾组织植入
Thorax. 2017 Feb;72(2):189-190. doi: 10.1136/thoraxjnl-2016-209068. Epub 2016 Sep 5.
3
Thoracic splenosis. Report of a case and review of the diagnostic workup.胸腔内脾组织植入。病例报告及诊断检查回顾
Breathe (Sheff). 2023 Dec;19(4):230156. doi: 10.1183/20734735.0156-2023. Epub 2024 Feb 13.
4
Posttraumatic thoracic splenosis in a 77-year-old patient after a motor vehicle accident.一名77岁患者在机动车事故后发生创伤后胸腔脾组织异位。
Respir Med Case Rep. 2023 Apr 26;44:101860. doi: 10.1016/j.rmcr.2023.101860. eCollection 2023.
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Thoracic Splenosis in the Setting of Abdominal Trauma.腹部创伤背景下的胸腔脾组织植入
Cureus. 2022 Aug 10;14(8):e27851. doi: 10.7759/cureus.27851. eCollection 2022 Aug.
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SPECT/CT with 99mTc labelled heat-denatured erythrocyte to detect thoracic and abdominal splenosis.SPECT/CT 联合 99mTc 标记加热变性红细胞检测胸腹部脾组织异位症。
Acta Biomed. 2020 Jul 6;91(4):e2020098. doi: 10.23750/abm.v91i4.9270.
7
Spleen in the thorax: A case report on traumatic diaphragmatic rupture.胸腔内脾脏:一例创伤性膈肌破裂病例报告
Int J Surg Case Rep. 2020;77:664-667. doi: 10.1016/j.ijscr.2020.11.018. Epub 2020 Nov 24.
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Benign splenic regrowth mistaken as recurrent renal cell carcinoma.被误诊为复发性肾细胞癌的脾脏良性再生
CMAJ. 2019 Dec 9;191(49):E1355-E1357. doi: 10.1503/cmaj.191128.
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Symptomatic Intrathoracic Splenosis More than Forty Years After a Gunshot Injury.枪伤四十多年后出现症状性胸腔内脾组织植入
Cureus. 2019 Oct 24;11(10):e5985. doi: 10.7759/cureus.5985.
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A case of thoracoabdominal splenosis.一例胸腹脾组织异位。
Radiol Case Rep. 2019 Nov 8;15(1):7-10. doi: 10.1016/j.radcr.2019.10.017. eCollection 2020 Jan.
Ann Ital Chir. 2016 Jul 29;87:S2239253X16025834.
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