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本文引用的文献

1
Panhypopituitarism presenting as life-threatening heart failure caused by an inherited microdeletion in 1q25 including LHX4.因 1q25 内包含 LHX4 的遗传性微缺失导致 panhypopituitarism 进而引发危及生命的心衰。
Pediatrics. 2012 Feb;129(2):e529-34. doi: 10.1542/peds.2010-3849. Epub 2012 Jan 9.
2
[Congenital hypopituitarism: report of 23 cases].[先天性垂体功能减退症：23例报告]
Rev Med Chil. 2008 Aug;136(8):996-1006. Epub 2008 Oct 7.
3
Neonatal detection of congenital hypothyroidism of central origin.新生儿期中枢性先天性甲状腺功能减退症的检测
J Clin Endocrinol Metab. 2005 Jun;90(6):3350-9. doi: 10.1210/jc.2004-2444. Epub 2005 Mar 22.
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A window of opportunity: the diagnosis of gonadotropin deficiency in the male infant.一个机会窗口：男婴促性腺激素缺乏症的诊断
J Clin Endocrinol Metab. 2005 May;90(5):3122-7. doi: 10.1210/jc.2004-2465. Epub 2005 Feb 22.
5
Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations.先天性孤立性促肾上腺皮质激素缺乏症：一种被低估的新生儿死亡原因，由TPIT基因突变所解释。
J Clin Endocrinol Metab. 2005 Mar;90(3):1323-31. doi: 10.1210/jc.2004-1300. Epub 2004 Dec 21.
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Neonatal identification of pituitary aplasia: a life-saving diagnosis. Review of five cases.新生儿垂体发育不全的识别：一项挽救生命的诊断。5例病例回顾。
Horm Res. 2004;62(1):10-6. doi: 10.1159/000077661. Epub 2004 Apr 1.
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Hypopituitarism in childhood.儿童垂体功能减退症。
Cancer Control. 2002 May-Jun;9(3):212-22. doi: 10.1177/107327480200900304.

A rare cause of respiratory distress and edema in neonate: Panhypopituitarism.

作者信息

Dursun Fatma, Kirmizibekmez Heves, Metin Fazilet

机构信息

Department of Pediatric Endocrinology, Umraniye Training and Research Hospital, Istanbul, Turkey.

Department of Neonatology, Erdem Hospital, Istanbul, Turkey.

出版信息

North Clin Istanb. 2017 Aug 26;4(2):188-191. doi: 10.14744/nci.2016.47450. eCollection 2017.

DOI:10.14744/nci.2016.47450
PMID:28971179
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5613269/
Abstract

Clinical presentation of hypopituitarism may be variable in the neonate. Symptoms are generally nonspecific, ranging from absent to severe, and even life-threatening, due to adrenocorticotrophic hormone deficiency. Presently described is a case of unexplained respiratory distress and edema in a neonate. Initial screening revealed panhypopituitarism. Respiratory distress improved after replacement treatment with hydrocortisone and thyroxine.

摘要