Radzivil G G, Roslyĭ I M
Ter Arkh. 1988;60(2):59-64.
A complex of blood enzymes (AST, ALT, AP, GTT) was studied in 84 patients with generalized forms of MI. The study showed that signs of liver involvement were noted in 15.4% of the patients on the 1st day of disease. Laboratory signs of cytolysis and cholestasis were revealed in most examinees on the 7th-15th day of disease during a dynamic follow-up. The most noticeable syndromes were revealed in young patients (30 persons) with brain edema (42.2%). Primary liver involvement (i. e. noted on admission to hospital) in 6 patients was associated with MI toxic effects, in 7 patients--with a severe concomitant pathology of the pulmonary and cardiovascular system. Delayed liver involvement was detected in 55.3% of the young patients and in half of the elderly patients. It was established that a course of disease was accompanied by the affection of many organs from the first days complicating the interpretation of enzymological data therefore requiring combined enzymological investigations.
对84例患有心肌梗死全身性形式的患者进行了一组血液酶（谷草转氨酶、谷丙转氨酶、碱性磷酸酶、γ-谷氨酰转肽酶）的研究。研究表明，在疾病第1天，15.4%的患者出现肝脏受累迹象。在动态随访过程中，大多数受检者在疾病第7 - 15天出现细胞溶解和胆汁淤积的实验室迹象。最明显的综合征出现在患有脑水肿的年轻患者（30人）中（42.2%）。6例患者的原发性肝脏受累（即入院时发现）与心肌梗死的毒性作用有关，7例患者与严重的肺和心血管系统合并病变有关。55.3%的年轻患者和一半的老年患者出现延迟性肝脏受累。已确定病程从最初几天起就伴有多个器官的病变，这使酶学数据的解读变得复杂，因此需要进行联合酶学研究。
