Aslam Bilal, Nisar Muhammad Atif, Khurshid Mohsin, Farooq Salamat Muhammad Khalid
Department of Microbiology, Government College University, Faisalabad, Pakistan.
College of Allied Health Professionals, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan.
Future Microbiol. 2017 Oct;12:1219-1237. doi: 10.2217/fmb-2017-0013. Epub 2017 Sep 15.
The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.
疏螺旋体病的再度流行表明伯氏疏螺旋体是一个持续存在的健康问题。这种螺旋体引发了一种名为莱姆病的全球公共卫生问题。伯氏疏螺旋体在其生命周期中面临着其传播媒介和宿主的多种环境条件。规避宿主免疫系统是伯氏疏螺旋体的一个显著特征。迄今为止，众多研究已经报道了这种病原体用于逃避宿主防御机制的各种机制。本综述试图整合这些信息，以描述伯氏疏螺旋体用于生存的免疫和分子方法。
