Jones R G, Grant P J, Brown D, Stickland M, Wiles P G
University Department of Chemical Pathology, Leeds General Infirmary, UK.
Diabet Med. 1988 Apr;5(3):253-5. doi: 10.1111/j.1464-5491.1988.tb00979.x.
Eight otherwise healthy insulin-dependent diabetic patients were subjected to controlled, symptomatic hypoglycaemia for 20 min (median glucose concentration 1.7 mmol/l, range 1.0-2.6 mmol/l). Concentrations of plasma adrenaline and plasma vasopressin were significantly increased, indicating normal counter-regulatory responses for these hormones. Plasma activities of the hepatic enzymes AST, ALT, LDH, GGT, and CK did not increase during or following the period of hypoglycaemia. Thus, abnormal plasma enzyme activities noted after clinical hypoglycaemia should be fully investigated, and not disregarded as due to the hypoglycaemic episode.
八名其他方面健康的胰岛素依赖型糖尿病患者经历了20分钟的控制性症状性低血糖（血糖浓度中位数为1.7毫摩尔/升，范围为1.0 - 2.6毫摩尔/升）。血浆肾上腺素和血浆血管加压素浓度显著升高，表明这些激素的正常反调节反应。低血糖期间及之后，肝酶AST、ALT、LDH、GGT和CK的血浆活性并未增加。因此，临床低血糖后出现的异常血浆酶活性应进行全面调查，而不应因低血糖发作而被忽视。
