Memorial Sloan Kettering Cancer Center, New York, NY.
J Oncol Pract. 2017 Feb;13(2):95-102. doi: 10.1200/JOP.2016.017608.
As the number of older patients with cancer is increasing, oncology disciplines are faced with the challenge of managing patients with multiple chronic conditions who have difficulty maintaining independence, who may have cognitive impairment, and who also may be more vulnerable to adverse outcomes. National and international societies have recommended that all older patients with cancer undergo geriatric assessment (GA) to detect unaddressed problems and introduce interventions to augment functional status to possibly improve patient survival. Several predictive models have been developed, and evidence has shown correlation between information obtained through GA and treatment-related complications. Comprehensive geriatric evaluations and effective interventions on the basis of GA may prove to be challenging for the oncologist because of the lack of the necessary skills, time constraints, and/or limited available resources. In this article, we describe how the Geriatrics Service at Memorial Sloan Kettering Cancer Center approaches an older patient with colon cancer from presentation to the end of life, show the importance of GA at the various stages of cancer treatment, and how predictive models are used to tailor the treatment. The patient's needs and preferences are at the core of the decision-making process. Development of a plan of care should always include the patient's preferences, but it is particularly important in the older patient with cancer because a disease-centered approach may neglect noncancer considerations. We will elaborate on the added value of co-management between the oncologist and a geriatric nurse practitioner and on the feasibility of adapting elements of this model into busy oncology practices.
随着癌症老年患者人数的增加,肿瘤学科面临着管理患有多种慢性疾病、难以保持独立性、认知障碍且更容易出现不良后果的患者的挑战。国家和国际社会建议所有癌症老年患者接受老年评估(GA),以发现未解决的问题,并引入干预措施来增强功能状态,从而可能提高患者的生存率。已经开发了几种预测模型,并且已经证明通过 GA 获得的信息与治疗相关的并发症之间存在相关性。由于缺乏必要的技能、时间限制和/或有限的可用资源,综合老年评估和基于 GA 的有效干预措施可能对肿瘤学家构成挑战。在本文中,我们描述了纪念斯隆凯特琳癌症中心老年科如何从患者就诊到生命末期来处理患有结肠癌的老年患者,展示了 GA 在癌症治疗各个阶段的重要性,以及如何使用预测模型来定制治疗。患者的需求和偏好是决策过程的核心。护理计划的制定应始终包括患者的偏好,但对于癌症老年患者尤为重要,因为以疾病为中心的方法可能会忽略非癌症因素。我们将详细阐述肿瘤学家和老年病护士从业者共同管理的附加价值,以及将该模式的要素适用于繁忙的肿瘤学实践的可行性。