University of Rochester School of Medicine and Dentistry, Rochester, NY; City of Hope National Medical Center, Duarte, CA; Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico; The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, Ontario, Canada; Leiden University Medical Center, Leiden, the Netherlands; The Royal Marsden NHS Foundation Trust, London, United Kingdom; Gustave Roussy, Villejuif; Institut Curie, PSL Research University, Paris, France; Memorial Sloan Kettering Cancer Center, New York, NY; and University Hospitals Leuven, Leuven, Belgium.
J Oncol Pract. 2018 Feb;14(2):85-94. doi: 10.1200/JOP.2017.026435.
Aging is a heterogeneous process. Most newly diagnosed cancers occur in older adults, and it is important to understand a patient's underlying health status when making treatment decisions. A geriatric assessment provides a detailed evaluation of medical, psychosocial, and functional problems in older patients with cancer. Specifically, it can identify areas of vulnerability, predict survival and toxicity, assist in clinical treatment decisions, and guide interventions in routine oncology practice; however, the uptake is hampered by limitations in both time and resources, as well as by a lack of expert interpretation. In this review, we describe the utility of geriatric assessment by using an illustrative case and provide a practical approach to geriatric assessment in oncology.
衰老是一个异质的过程。大多数新诊断的癌症发生在老年人中,因此在制定治疗决策时,了解患者的潜在健康状况非常重要。老年评估为患有癌症的老年患者提供了对医疗、心理社会和功能问题的详细评估。具体来说,它可以识别脆弱领域,预测生存和毒性,协助临床治疗决策,并指导常规肿瘤学实践中的干预措施;但是,由于时间和资源的限制以及缺乏专家解释,其应用受到阻碍。在这篇综述中,我们通过一个说明性的案例描述了老年评估的效用,并提供了一种实用的肿瘤学老年评估方法。