Funaro Kimberly, Drukteinis Jennifer, Falcon Shannon
From the Department of Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa Florida.
South Med J. 2017 Oct;110(10):607-613. doi: 10.14423/SMJ.0000000000000708.
Breast cancer screening with mammography reduces breast cancer mortality; however, diverging recommendations regarding screening have caused controversy. The emerging technology of digital breast tomosynthesis (DBT) may soon become the mainstay of breast cancer screening. We present recommendations for breast cancer screening based on guidelines. A PubMed literature review was performed and the results from five large clinical studies comparing the efficacy of digital mammography alone versus digital mammography with DBT are examined. We emphasize the importance of annual screening to reduce breast cancer mortality. Our review of the literature demonstrates that DBT increases cancer detection rates and reduces callbacks. Additional research is needed to determine whether the increased cancer detection rates are associated with a decrease in mortality.
乳腺钼靶筛查可降低乳腺癌死亡率；然而，关于筛查的不同建议引发了争议。数字乳腺断层合成（DBT）这一新兴技术可能很快会成为乳腺癌筛查的主要手段。我们基于指南提出乳腺癌筛查建议。进行了PubMed文献综述，并审视了五项比较单纯数字乳腺钼靶与数字乳腺钼靶联合DBT疗效的大型临床研究结果。我们强调年度筛查对于降低乳腺癌死亡率的重要性。我们的文献综述表明，DBT可提高癌症检出率并减少召回率。还需要进一步研究以确定癌症检出率的提高是否与死亡率降低相关。
