Shafique Michael R, Lee Marie Catherine, Han Hyo Sook
From the H. Lee Moffitt Cancer Center and Research Institute, Breast Oncology Program, Tampa, Florida.
South Med J. 2017 Oct;110(10):627-631. doi: 10.14423/SMJ.0000000000000702.
Pregnancy-associated breast cancer is defined as invasive breast cancer diagnosed during gestation, within 1 year postpartum, or during lactation. Of particular interest is the treatment of invasive breast cancer during gestation; standard treatment protocols must take into account the health of the fetus. This article reviews the literature and emerging data regarding the treatment of pregnancy-associated breast cancer. Existing staging and treatment practices need slight modification in the setting of pregnancy. The timing of surgery and the administration of cytotoxic chemotherapy must take into account age of gestation, but these modalities are safe in pregnancy.
妊娠相关乳腺癌被定义为在妊娠期、产后1年内或哺乳期诊断出的浸润性乳腺癌。妊娠期浸润性乳腺癌的治疗尤其值得关注；标准治疗方案必须考虑胎儿的健康状况。本文综述了有关妊娠相关乳腺癌治疗的文献和新出现的数据。在妊娠情况下，现有的分期和治疗方法需要稍作调整。手术时机和细胞毒性化疗的给药必须考虑孕周，但这些方法在妊娠期间是安全的。
