Bridge between type 1 diabetes in mouse and man.
作者信息
Zeng Defu
机构信息
Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010
出版信息
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10821-10823. doi: 10.1073/pnas.1715058114. Epub 2017 Oct 2.
Abstract
摘要
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Bridge between type 1 diabetes in mouse and man.小鼠与人类1型糖尿病之间的桥梁。
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10821-10823. doi: 10.1073/pnas.1715058114. Epub 2017 Oct 2.
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Failure to transfer diabetes mellitus from man to mouse.未能将糖尿病从人类转移至小鼠。
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How viral infections enhance or prevent type 1 diabetes-from mouse to man.病毒感染如何促进或预防1型糖尿病——从小鼠到人类
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Mouse and man: multiple genes and multiple autoantigens in the aetiology of type I DM and related autoimmune disorders.人与鼠：1型糖尿病及相关自身免疫性疾病病因中的多个基因和多种自身抗原
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Passive transfer of lymphocytes from diabetic man to athymic mouse.将糖尿病男性的淋巴细胞被动转移至无胸腺小鼠体内。
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Insulin as an autoantigen in NOD/human diabetes.胰岛素作为非肥胖型糖尿病/人类糖尿病中的自身抗原。
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[Diabetes mellitus and cellular immunity].[糖尿病与细胞免疫]
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Contribution of class III MHC to susceptibility to type 1 diabetes in the NOD mouse.Ⅲ类主要组织相容性复合体对非肥胖糖尿病小鼠1型糖尿病易感性的影响
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Target antigens in autoimmune diabetes: pancreatic gangliosides.自身免疫性糖尿病中的靶抗原：胰腺神经节苷脂。
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[Comparative study of retinopathy in C57BL/6 and eNOS-knockout mouse models of type 1 diabetes mellitus].[C57BL/6和1型糖尿病eNOS基因敲除小鼠模型视网膜病变的比较研究]
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T1D patient-derived hematopoietic stem cells are programmed to generate Tph, Tfh, and autoimmunity-associated B cell subsets in human immune system mice.1 型糖尿病患者来源的造血干细胞在人免疫系统小鼠中被编程生成 Tph、Tfh 和与自身免疫相关的 B 细胞亚群。
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Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice.半相合混合嵌合体治愈已建立的 1 型糖尿病小鼠的自身免疫。
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MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice.MHC 错配混合嵌合体恢复 NOD 小鼠中非交叉反应性自身反应性 T 细胞的外周耐受。
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本文引用的文献
1
Type 1 diabetes induction in humanized mice.人源化小鼠的 1 型糖尿病诱导。
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10954-10959. doi: 10.1073/pnas.1710415114. Epub 2017 Sep 5.
2
Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.1 型糖尿病中针对核糖体胰岛素基因产物缺陷的自身免疫。
Nat Med. 2017 Apr;23(4):501-507. doi: 10.1038/nm.4289. Epub 2017 Feb 27.
3
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.1型糖尿病中的致病性CD4 T细胞识别由肽融合形成的表位。
Science. 2016 Feb 12;351(6274):711-4. doi: 10.1126/science.aad2791.
4
The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes.非肥胖糖尿病（NOD）小鼠模型在自身免疫性糖尿病中的重要性。
J Autoimmun. 2016 Jan;66:76-88. doi: 10.1016/j.jaut.2015.08.019. Epub 2015 Sep 26.
5
Functional cytotoxic T lymphocytes against IGRP206-214 predict diabetes in the non-obese diabetic mouse.针对IGRP206 - 214的功能性细胞毒性T淋巴细胞可预测非肥胖糖尿病小鼠是否患糖尿病。
Immunol Cell Biol. 2014 Aug;92(7):640-4. doi: 10.1038/icb.2014.29. Epub 2014 Apr 29.
6
A humanized mouse model of autoimmune insulitis.自身免疫性胰岛炎的人源化小鼠模型。
Diabetes. 2014 May;63(5):1712-24. doi: 10.2337/db13-1141. Epub 2014 Jan 29.
7
Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes.识别胰岛素不稳定肽段的致病性 CD4⁺ T 细胞可绕过局部淋巴结直接募集到胰岛。
J Exp Med. 2013 Oct 21;210(11):2403-14. doi: 10.1084/jem.20130582. Epub 2013 Oct 14.
8
Type 1 diabetes.1 型糖尿病。
Lancet. 2014 Jan 4;383(9911):69-82. doi: 10.1016/S0140-6736(13)60591-7. Epub 2013 Jul 26.
9
The problems and promises of research into human immunology and autoimmune disease.人类免疫学与自身免疫性疾病研究的问题与前景
Nat Med. 2012 Jan 6;18(1):48-53. doi: 10.1038/nm.2626.
10
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.胰岛自身反应性 CD8 T 细胞在近期发病和长期 1 型糖尿病患者胰岛炎病变中的示踪。
J Exp Med. 2012 Jan 16;209(1):51-60. doi: 10.1084/jem.20111187. Epub 2012 Jan 2.
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