Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.
Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.
Clin Ther. 2017 Nov;39(11):2322-2330. doi: 10.1016/j.clinthera.2017.09.008. Epub 2017 Sep 30.
The purpose of this study was to investigate the effects of stellate ganglion block (SGB) on gastrointestinal function after thoracolumbar spinal surgery.
Forty patients with thoracolumbar fracture scheduled for posterior spinal surgery were randomly assigned to 2 groups: ultrasound-guided SGB or sham (control group). After induction, ultrasound-guided SGB (n = 20) or a sham procedure (n = 20) was conducted with a 6-mL injection of 1% lidocaine or 0.9% saline, respectively. Primary outcomes were postoperative gastrointestinal function, including auscultation of bowel sounds, incidence and degree of abdominal bloating, flatus time, and paralytic ileus.
Patients in the SGB group had better gastrointestinal function compared with those in the sham (control) group, as indicated by more regular bowel sounds at 24 and 36 hours postoperatively (80% vs 40%, P = 0.024, and 95% vs 60%, P = 0.023), lesser abdominal bloating (10% vs 45%, P = 0.034), and slightly shorter flatus time (mean [SD], 12.0 [4.4] vs 14.7 [4.6] hours, P = 0.068). Survival analysis based on regular bowel sounds found a significant difference between the 2 groups (P = 0.004). In addition, more patients had higher satisfaction after SGB (85% vs 45%, P = 0.020). No postoperative ileus or mortality occurred.
In this preliminary study, ultrasound-guided SGB accelerated the return of gastrointestinal transit, alleviated bowel symptoms, and improved patient satisfaction after thoracolumbar spinal surgery. chictr.org.cn identifier: ChiCTR-TRC-14004289.
本研究旨在探讨星状神经节阻滞(SGB)对胸腰椎脊柱手术后胃肠功能的影响。
40 例拟行后路脊柱手术的胸腰椎骨折患者随机分为 2 组:超声引导 SGB 组(n = 20)或假手术(对照组)组(n = 20)。诱导后,分别用 1%利多卡因 6mL 或 0.9%生理盐水行超声引导 SGB 或假手术。主要结局为术后胃肠功能,包括肠鸣音听诊、腹胀发生率和程度、肛门排气时间和麻痹性肠梗阻。
SGB 组患者胃肠功能优于对照组,术后 24 小时和 36 小时肠鸣音更规则(80%比 40%,P = 0.024;95%比 60%,P = 0.023),腹胀程度较轻(10%比 45%,P = 0.034),肛门排气时间略短(平均[标准差],12.0[4.4]比 14.7[4.6]小时,P = 0.068)。基于肠鸣音规则的生存分析发现 2 组间有显著差异(P = 0.004)。此外,SGB 后更多患者满意度更高(85%比 45%,P = 0.020)。无术后肠梗阻或死亡发生。
在本初步研究中,超声引导 SGB 可加速胸腰椎脊柱手术后胃肠转运恢复,缓解肠道症状,提高患者满意度。