Yuan Xueling, Tang Yijie, Xie Xiyuan, Qiu Jiapeng, Han Yupeng, Ke Peng, Zheng Chengjie, Zeng Kai, Wu Xiaodan
Shengli Clinical Medical College of Fujian Medical University, Department of Anesthesiology, Fujian Provincial Hospital, Fuzhou, Fujian, China.
Fuzhou University Affiliated Provincial Hospital, Department of Anesthesiology, School of Medicine, Fuzhou University, Fuzhou, Fujian, China.
Front Med (Lausanne). 2025 Jun 9;12:1561512. doi: 10.3389/fmed.2025.1561512. eCollection 2025.
This study aims to observe whether right-sided stellate ganglion block (SGB) before surgery can improve early postoperative recovery quality in peri-menopausal women undergoing elective gynecological laparoscopic surgery.
Ninety-four peri-menopausal women, who meet the inclusion criteria, scheduled for gynecological laparoscopic surgery were selected (Trial Registration: ChiCTR2200057907, March 21, 2022). They were randomly assigned into two groups (Group S and Group C). Group S received right-sided SGB under ultrasound guidance, combined with tracheal intubation and general anesthesia, with an injection of 4 mL of 0.2% ropivacaine. Group C underwent only ultrasound scanning combined with tracheal intubation and general anesthesia. The primary outcome was postoperative recovery quality at 24 h, assessed using the 40-item Quality of Recovery (QoR-40) questionnaire. Secondary outcomes included: (1) Heart rate (HR) and Mean Arterial Pressure (MAP); (2) Resting pain scores; (3) Recovery of gastrointestinal function postoperatively; (4) Postoperative adverse reactions within 24 h.
At 24 h postoperative, Group S had a higher QoR-40 total score compared to Group C with a corrected mean difference of 12.50. Significant differences in HR were noted at T3, T5, and T6, and in MAP at T2, T4, T6, and T7. The resting pain scores at 4, 8, and 12 h postoperatively differed significantly between the two groups. (4) Compared with Group C, Group S had a shorter time to first flatus and a shorter time to the first return of bowel sounds. The incidence of postoperative abdominal distension was lower in Group S compared to the Group C. (5) The incidence of postoperative nausea, vomiting, headache, shoulder pain, and throat pain was lower in Group S than Group C, with statistically significant differences.
Preoperative single-session stellate ganglion block improves 24-h postoperative recovery in peri-menopausal women undergoing gynecological laparoscopic surgery by alleviating pain, stabilizing hemodynamics, promoting gastrointestinal recovery, and reducing postoperative adverse reactions.
www.chictr.org.cn, identifier ChiCTR2200057907.
本研究旨在观察术前右侧星状神经节阻滞（SGB）是否能改善择期妇科腹腔镜手术围绝经期女性术后早期恢复质量。
选取94例符合纳入标准、计划行妇科腹腔镜手术的围绝经期女性（试验注册号：ChiCTR2200057907，2022年3月21日）。她们被随机分为两组（S组和C组）。S组在超声引导下接受右侧SGB，联合气管插管和全身麻醉，注射4 mL 0.2%罗哌卡因。C组仅接受超声扫描联合气管插管和全身麻醉。主要结局是术后24小时的恢复质量，采用40项恢复质量（QoR-40）问卷进行评估。次要结局包括：（1）心率（HR）和平均动脉压（MAP）；（2）静息疼痛评分；（3）术后胃肠功能恢复情况；（4）术后24小时内的不良反应。
术后24小时，S组的QoR-40总分高于C组，校正平均差值为12.50。在T3、T5和T6时HR有显著差异，在T2、T4、T6和T7时MAP有显著差异。两组术后4、8和12小时的静息疼痛评分有显著差异。（4）与C组相比，S组首次排气时间和首次肠鸣音恢复时间更短。S组术后腹胀发生率低于C组。（5）S组术后恶心、呕吐、头痛、肩痛和咽痛的发生率低于C组，差异有统计学意义。
术前单次星状神经节阻滞通过减轻疼痛、稳定血流动力学、促进胃肠恢复和减少术后不良反应，改善了接受妇科腹腔镜手术的围绝经期女性术后24小时的恢复情况。
