Monte Carlo modelling of live-timed anticoincidence (LTAC) counting for Cu-64.
作者信息
Bergeron Denis E, Fitzgerald Ryan
机构信息
Physical Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899-8642, USA.
Physical Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899-8642, USA.
出版信息
Appl Radiat Isot. 2018 Apr;134:280-285. doi: 10.1016/j.apradiso.2017.09.032. Epub 2017 Sep 23.
Abstract
The radionuclide copper-64 is a promising candidate for nuclear medicine, but its complex decay creates challenges in the primary standardization of its activity. Monte Carlo simulations of live-timed anticoincidence (LTAC) counting of Cu were used to calculate corrections to extrapolation intercepts, resulting in improved activity determinations. A small correction (-0.33%) to the linear extrapolation of LTAC data acquired with a γ-gate over the 1346keV gamma peak was determined. We discuss the physical origin of the correction. We also use experimental data to demonstrate a Monte Carlo scaling that allows for inclusion of data acquired with a γ-gate set over the annihilation photon peak(s).
摘要
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